2-amino-3,5-dichloro-N-hydroxybenzenecarboxamide

Base Information

• Chemical Name: 2-amino-3,5-dichloro-N-hydroxybenzenecarboxamide
• CAS No.: 1130-71-8
• Molecular Formula: C7H6Cl2N2O2
• Molecular Weight: 221.04100
• Mol file: 1130-71-8.mol

Synonyms:

Chemical Property of 2-amino-3,5-dichloro-N-hydroxybenzenecarboxamide

Chemical Property:

• PSA: 75.35000
• LogP: 2.66670

Purity/Quality:

95% ^*data from raw suppliers

2-Amino-3,5-dichloro-N-hydroxybenzenecarboxamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-amino-3,5-dichloro-N-hydroxybenzenecarboxamide

There total 3 articles about 2-amino-3,5-dichloro-N-hydroxybenzenecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

→ 2-Amino-3,5-dichloro-N-hydroxy-benzamide (1130-71-8)

Guidance literature:

With hydroxylamine hydrochloride; sodium methylate; In methanol; for 96h; Ambient temperature;

DOI:10.1021/je00032a042

Reference yield:

3,5-dichloroantranilic acid (2789-92-6) → 2-Amino-3,5-dichloro-N-hydroxy-benzamide (1130-71-8)

Guidance literature:

3,5-dichloroantranilic acid; With dmap; 1-hydroxybenzotriazole-6-sulfonamidomethyl polystyrene resin; diisopropyl-carbodiimide; In dichloromethane; N,N-dimethyl-formamide; for 2h;

With hydroxylamine; In tetrahydrofuran; methanol; for 4h;

DOI:10.1039/b505525c

Reference yield:

→ 2-Amino-3,5-dichloro-N-hydroxy-benzamide (1130-71-8)

Guidance literature:

Aus entspr. Ester u. Hydroxylamin;

upstream raw materials:

3,5-dichloroantranilic acid

Refernces

• 1、 Eckstein, Zygmunt,Jadach, Tadeusz,Lipczynska-Kochany, Ewa. "Facile Synthesis of Benzimidazol-2-one Derivatives by Modified Lossen Rearrangement". . p. 279 - 281. Retrieved 2007/10/02.