4-(2,4-Difluorophenyl)phenol

Base Information Edit

Chemical Name:4-(2,4-Difluorophenyl)phenol
CAS No.:59089-68-8
Molecular Formula:C12H8F2O
Molecular Weight:206.192
Hs Code.:2907199090
European Community (EC) Number:261-599-4
UNII:5A4JM6LXT5
DSSTox Substance ID:DTXSID60207831
Nikkaji Number:J308.616J
Wikidata:Q72463965
ChEMBL ID:CHEMBL121812
Mol file:59089-68-8.mol

Synonyms:59089-68-8;4-(2,4-difluorophenyl)phenol;2',4'-Difluoro-[1,1'-biphenyl]-4-ol;2',4'-Difluoro-biphenyl-4-ol;[1,1'-Biphenyl]-4-ol, 2',4'-difluoro-;2',4'-Difluoro(1,1'-biphenyl)-4-ol;EINECS 261-599-4;5A4JM6LXT5;2',4'-DIFLUORO-4-HYDROXY BIPHENYL;2',4'-Difluoro-4-hydroxybiphenyl;2',4'-difluoro[1,1'-biphenyl]-4-ol;2',4'-difluorobiphenyl-4-ol;(1,1'-BIPHENYL)-4-OL, 2',4'-DIFLUORO-;2',4-DIFLUORO-4-HYDROXY BIPHENYL;UNII-5A4JM6LXT5;SCHEMBL412535;CHEMBL121812;DTXSID60207831;2',4'-Difluoro-4-hydroxybipheny;4-(2',4'-difluorophenyl)phenol;2',4'-difluoro-4-hydroxy-biphenyl;MFCD03414359;AKOS016001018;AB92540;2,4-DIFLUORO-4-HYDROXYBIPHENYL;2',4'-Difluoro-1,1'-biphenyl-4-ol;AS-61301;CS-0157456;2\',4\'-Difluoro-[1,1\'-biphenyl]-4-ol;D83814;A832149

Suppliers and Price of 4-(2,4-Difluorophenyl)phenol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2'',4''-Difluorobiphenyl-4-ol
250mg
$ 160.00

SynQuest Laboratories
2',4'-Difluoro-4-hydroxybiphenyl
1 g
$ 155.00

SynQuest Laboratories
2',4'-Difluoro-4-hydroxybiphenyl
250 mg
$ 55.00

Labseeker
4-(2,4-Difluorophenyl)phenol 95
5g
$ 1380.00

Crysdot
2',4'-Difluoro-[1,1'-biphenyl]-4-ol 95+%
5g
$ 299.00

Chemenu
2'',4''-Difluoro-[1,1''-biphenyl]-4-ol 95%
5g
$ 282.00

AOBChem
4-(2,4-difluorophenyl)phenol 97%
500mg
$ 59.00

AOBChem
4-(2,4-difluorophenyl)phenol 97%
10g
$ 476.00

American Custom Chemicals Corporation
2',4'-DIFLUORO-4-HYDROXYBIPHENYL 95.00%
5G
$ 1100.02

American Custom Chemicals Corporation
2',4'-DIFLUORO-4-HYDROXYBIPHENYL 95.00%
1G
$ 708.48

Total 26 raw suppliers

Chemical Property of 4-(2,4-Difluorophenyl)phenol Edit

Chemical Property:

Boiling Point:289.5 °C at 760 mmHg
PKA:9.30±0.30(Predicted)
Flash Point:128.9 °C
PSA：20.23000
Density:1.276 g/cm³
LogP:3.33740
Storage Temp.:Inert atmosphere,Room Temperature
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:206.05432120
Heavy Atom Count:15
Complexity:202

Purity/Quality:

99% ^*data from raw suppliers

2'',4''-Difluorobiphenyl-4-ol ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=C(C=C(C=C2)F)F)O
Uses 2'',4''-Difluorobiphenyl-4-ol (Diflunisal EP Impurity B) is an intermediate in the synthesis of labelled Diflunisal (D445752) which is an analgesic; anti-inflammatory.

Technology Process of 4-(2,4-Difluorophenyl)phenol

There total 10 articles about 4-(2,4-Difluorophenyl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 540-38-5
p-Iodophenol

: 144025-03-6
2,4-difluorophenylboronic acid

: 59089-68-8
4-(2,4-difluorophenyl)-phenol

Guidance literature:: With potassium carbonate; palladium⁽⁰⁾bis(tricyclohexylphosphine); In water; N,N-dimethyl-formamide; Inert atmosphere; Reflux;