Technology Process of 19-Norpregn-4-ene-3,20-dione, 21-hydroxy-
There total 64 articles about 19-Norpregn-4-ene-3,20-dione, 21-hydroxy- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
methanol; water; potassium carbonate;
In
dichloromethane;
for 1.33333h;
- Guidance literature:
-
With
calcium carbonate; mercury dichloride;
In
methanol; water;
for 5h;
Heating;
DOI:10.1021/jo01310a028
- Guidance literature:
-
Multi-step reaction with 9 steps
1: hypobromous acid
2: Pb(OAc)4, I2 / Irradiation
3: hydrolysis
4: 1.) BF3*Et2O / 1.) C6H6, MeOH, room temperature, 20 min, 2.) 5 h
5: Jones reagent / acetone / 5 °C
6: NaOAc / methanol / 1 h / Heating
7: 111 mg / Zn, AcOH / propan-2-ol / 3 h / Heating
8: 55 mg / pyridinuim chlorochromate / CH2Cl2 / 0.5 h / Ambient temperature
9: 20 mg / KOH / methanol / 1 h / Heating
With
lead(IV) acetate; potassium hydroxide; jones reagent; boron trifluoride diethyl etherate; iodine; sodium acetate; hypobromous acid; acetic acid; pyridinium chlorochromate; zinc;
In
methanol; dichloromethane; isopropyl alcohol; acetone;