6,8-Dioxa-3,11-diazatridecanedioic acid, 7-(4,5-dimethoxy-2-nitrophenyl)-3,11-bis(2-ethoxy-2-oxoethyl)-, diethyl ester

Base Information

• Chemical Name: 6,8-Dioxa-3,11-diazatridecanedioic acid, 7-(4,5-dimethoxy-2-nitrophenyl)-3,11-bis(2-ethoxy-2-oxoethyl)-, diethyl ester
• CAS No.: 113430-85-6
• Molecular Formula: C₂₉H₄₅N₃O₁₄
• Molecular Weight: 659.688
• Mol file: 113430-85-6.mol

Synonyms:

Chemical Property of 6,8-Dioxa-3,11-diazatridecanedioic acid, 7-(4,5-dimethoxy-2-nitrophenyl)-3,11-bis(2-ethoxy-2-oxoethyl)-, diethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6,8-Dioxa-3,11-diazatridecanedioic acid, 7-(4,5-dimethoxy-2-nitrophenyl)-3,11-bis(2-ethoxy-2-oxoethyl)-, diethyl ester

There total 3 articles about 6,8-Dioxa-3,11-diazatridecanedioic acid, 7-(4,5-dimethoxy-2-nitrophenyl)-3,11-bis(2-ethoxy-2-oxoethyl)-, diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

Diethyl iminodiacetate (6290-05-7) + o-nitroveratraldehyde bis(2-iodoethyl) acetal (113430-84-5) → o-nitroveratraldehyde bis<2-(bis(ethoxycarbonyl)methyl)amino)ethyl> acetal (113430-85-6)

Guidance literature:

for 192h; under 258574 Torr;

DOI:10.1021/jo00244a022

Reference yield:

6-nitroveratraldehyde (20357-25-9) → o-nitroveratraldehyde bis<2-(bis(ethoxycarbonyl)methyl)amino)ethyl> acetal (113430-85-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 62 percent / tosic acid / toluene / 8 h / Heating

2: 100 percent / NaI / acetone / 1 h / Heating

3: 65 percent / 192 h / 258574 Torr

With toluene-4-sulfonic acid; sodium iodide; In acetone; toluene;

DOI:10.1021/jo00244a022

Reference yield:

o-nitroveratraldehyde bis(2-bromoethyl) acetal (113430-93-6) → o-nitroveratraldehyde bis<2-(bis(ethoxycarbonyl)methyl)amino)ethyl> acetal (113430-85-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / NaI / acetone / 1 h / Heating

2: 65 percent / 192 h / 258574 Torr

With sodium iodide; In acetone;

DOI:10.1021/jo00244a022

upstream raw materials:

Diethyl iminodiacetate

o-nitroveratraldehyde bis(2-iodoethyl) acetal

6-nitroveratraldehyde

o-nitroveratraldehyde bis(2-bromoethyl) acetal

Refernces