2-Methoxyphenylhydrazine Hydrochloride

Base Information

• Chemical Name: 2-Methoxyphenylhydrazine Hydrochloride
• CAS No.: 6971-45-5
• Molecular Formula: C7H10N2O^.HCl
• Molecular Weight: 174.63
• Hs Code.: 29280000
• European Community (EC) Number: 230-199-1
• NSC Number: 66535
• Mol file: 6971-45-5.mol

Synonyms:6971-45-5;(2-methoxyphenyl)hydrazine Hydrochloride;2-Methoxyphenylhydrazine Hydrochloride;57396-67-5;2-Methoxyphenylhydrazine HCL;2-Methoxyphenylhydrazine, HCl;Hydrazine, (2-methoxyphenyl)-, monohydrochloride;(2-Methoxyphenyl)hydrazine HCl;(2-methoxyphenyl)hydrazine;hydrochloride;Hydrazine, (2-methoxyphenyl)-, hydrochloride;MFCD00035456;(2-Methoxyphenyl)hydrazine hydrochloride(1:x);EINECS 230-199-1;2-Hydrazinoanisole Hydrochloride;(2-Methoxyphenyl)hydrazine monohydrochloride;1-(2-Methoxyphenyl)hydrazine hydrochloride;C7H10N2O.ClH;Cambridge id 5511514;SCHEMBL120339;HECSHXUNOVTAIJ-UHFFFAOYSA-N;NSC66535;NSC-66535;o-Methoxyphenylhydrazine hydrochloride;2-methoxyphenyl hydrazine hydrochloride;AKOS001475852;(2-methoxy-phenyl)-hydrazine HCl salt;CS-W002166;GS-3180;(2-methoxyphenyl)hydrazine.hydrochloride;(2-Methoxyphenyl)hydrazine xhydrochloride;AC-18226;(2-Methoxy-phenyl)-hydrazine hydrochloride;A9219;AM20060226;FT-0612864;FT-0746211;M0617;EN300-67558;1-(2-methoxyphenyl)hydrazine hydrogen chloride;A21626;(2-METHOXY-PHENYL)-HYDRAZINE, HYDROCHLORIDE;Q-101298;F2147-0628

Chemical Property of 2-Methoxyphenylhydrazine Hydrochloride

Chemical Property:

• Vapor Pressure: 0.0014mmHg at 25°C
• Melting Point: 118-120 °C
• Boiling Point: 263.5 °C at 760 mmHg
• Flash Point: 113.2 °C
• PSA: 47.28000
• LogP: 2.55610
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Water Solubility.: Soluble in water
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 174.0559907
• Heavy Atom Count: 11
• Complexity: 97.6

Purity/Quality:

99% ^*data from raw suppliers

2-Methoxyphenylhydrazine Hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=CC=C1NN.Cl

Technology Process of 2-Methoxyphenylhydrazine Hydrochloride

There total 1 articles about 2-Methoxyphenylhydrazine Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methoxy-phenylamine (90-04-0) → 2-methoxyphenylhydrazine hydrochloride (6971-45-5,57396-67-5)

Guidance literature:

2-methoxy-phenylamine; With hydrogenchloride; sodium nitrite; In water; at 0 - 5 ℃;

With hydrogenchloride; tin(ll) chloride; In water; at 0 - 20 ℃;

DOI:10.1016/j.ejmech.2010.07.038

Reference yield: 95.0%

2-methoxyphenylhydrazine hydrochloride (6971-45-5,57396-67-5) + benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → 2-methoxy-1,1'-biphenyl (86-26-0,292625-97-9)

Guidance literature:

With potassium permanganate; acetic acid; Heating;

DOI:10.1016/j.tet.2008.05.004

Reference yield: 95.0%

3-Aminocrotononitrile (1118-61-2) + 2-methoxyphenylhydrazine hydrochloride (6971-45-5,57396-67-5) → 2-(2-methoxyphenyl)-5-methyl-2H-pyrazol-3-ylamine (91331-85-0)

Guidance literature:

3-Aminocrotononitrile; 2-methoxyphenylhydrazine hydrochloride; With hydrogenchloride; In water; at 100 ℃; for 18h;

With sodium hydroxide; In water; pH=> 12;

upstream raw materials:

2-methoxy-phenylamine

Downstream raw materials:

4-{[1-(2-methoxy-phenyl)-3-methyl-5-oxo-1,5-dihydro-pyrazol-4-ylidene]-hydrazino}-N-thiazol-2-yl-benzenesulfonamide

4-Hydroxy-3-{1-[(2-methoxy-phenyl)-hydrazono]-ethyl}-chromen-2-one

2-<2-(2-methoxyphenyl)hydrazino>tropone

4-isopropenyl-2-<2-(2-methoxyphenyl)hydrazino>tropone

Refernces

• 1、 Xu, Renbo,Xia, Rui,Luo, Ming,Xu, Xiaoyong,Cheng, Jiagao,Shao, Xusheng,Li, Zhong. "Design, synthesis, crystal structures, and insecticidal activities of eight-membered azabridge neonicotinoid analogues". . p. 381 - 390. Retrieved 2014/02/14.