(2-Nitro-phenyl)-phenyl-methanone

Base Information

• Chemical Name: (2-Nitro-phenyl)-phenyl-methanone
• CAS No.: 2243-79-0
• Molecular Formula: C13H9NO3
• Molecular Weight: 227.219
• Hs Code.: 2914700090
• DSSTox Substance ID: DTXSID20176958
• Nikkaji Number: J96.221J
• Wikidata: Q83047284
• Mol file: 2243-79-0.mol

Synonyms:2243-79-0;(2-Nitro-phenyl)-phenyl-methanone;(2-nitrophenyl)(phenyl)methanone;2-Nitrobenzophenone;(2-nitrophenyl)-phenylmethanone;Methanone, (2-nitrophenyl)phenyl-;(2-Nitrophenyl)phenylmethanone;Methanone, (nitrophenyl)phenyl-;Nitrobenzophenone;2-Nitro-benzophenon;2-nitro-benzophenone;SCHEMBL411359;DTXSID20176958;UJHSIDUUJPTLDY-UHFFFAOYSA-N;CAA24379;MFCD00033883;STK082795;AKOS005392540;SB35582;AM803545;AS-19635;CS-0312874;FT-0697013

Chemical Property of (2-Nitro-phenyl)-phenyl-methanone

Chemical Property:

• Vapor Pressure: 7.48E-07mmHg at 25°C
• Refractive Index: 1.614
• Boiling Point: 407.6 °C at 760 mmHg
• Flash Point: 202.4 °C
• PSA: 62.89000
• Density: 1.266 g/cm³
• LogP: 3.34900
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 227.058243149
• Heavy Atom Count: 17
• Complexity: 292

Purity/Quality:

98%Min ^*data from raw suppliers

(2-Nitro-phenyl)-phenyl-methanone ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)C2=CC=CC=C2[N+](=O)[O-]

Technology Process of (2-Nitro-phenyl)-phenyl-methanone

There total 43 articles about (2-Nitro-phenyl)-phenyl-methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

(2-nitrophenyl)phenylmethanol (5176-12-5) → 2-nitrobenzophenone (2243-79-0)

Guidance literature:

With manganese(IV) oxide; In dichloromethane; for 20h; Heating;

DOI:10.3987/com-03-9926

Reference yield: 90.0%

(R)-2-nitrobenzilic acid (654068-45-8) → 2-nitrobenzophenone (2243-79-0)

Guidance literature:

With oxygen; pivalaldehyde; [1,2-C₆H₄(NCOCONMe)2-Co(III)]^(1-)*NMe₄⁽¹⁺⁾; In acetonitrile;

DOI:10.1055/s-2003-42123

Reference yield: 89.0%

2-nitrobenzyl chloride (610-14-0) + benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → 2-nitrobenzophenone (2243-79-0)

Guidance literature:

With iron(III) chloride; In dichloromethane; at -5 - 0 ℃; for 4h; Reagent/catalyst; Concentration; Inert atmosphere;

upstream raw materials:

2-nitrodiphenylmethane

2-Nitro-benzhydrol

2-nitro-benzaldehyde

2-nitrobenzyl chloride

Downstream raw materials:

2,2'-dinitro-benzophenone

o,m'-Dinitrobenzophenone

o-nitrophenyl p-nitrophenyl ketone

N,N'-bis-(2-benzyl-phenyl)-hydrazine

Refernces

• 1、 Nagaki, Aiichiro,Sasatsuki, Kengo,Ishiuchi, Satoshi,Miuchi, Nobuyuki,Takumi, Masahiro,Yoshida, Jun-ichi. "Synthesis of Functionalized Ketones from Acid Chlorides and Organolithiums by Extremely Fast Micromixing". supporting information. p. 4946 - 4950. Retrieved 2019/03/21.
• 2、 -. "Method for preparing aromatic ketone in aqueous phase". Paragraph 0046-0049. . Retrieved 2018/04/26.