MOMORDINIC

Base Information

• Chemical Name: MOMORDINIC
• CAS No.: 96990-18-0
• Molecular Formula: C41H64O13
• Molecular Weight: 764.951
• Hs Code.: 29389090
• Mol file: 96990-18-0.mol

Synonyms:(3β)-28-Hydroxy-28-oxoolean-12-en-3-yl 3-O-β-D-xylopyranosyl-β-D-glucopyranosiduronic acid;

Chemical Property of MOMORDINIC

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 238-240 °C
• Refractive Index: 1.605
• Boiling Point: 886.229 °C at 760 mmHg
• PKA: 2.75±0.70(Predicted)
• Flash Point: 263.092 °C
• PSA: 212.67000
• Density: 1.35 g/cm³
• LogP: 3.61340
• Storage Temp.: 2-8°C
• Solubility.: Methanol (Slightly, Heated, Sonicated), Pyridine (Slightly)

Purity/Quality:

99%, ^*data from raw suppliers

Momordin 1c ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Mormodin Ic is used as an anti-cancer agent, and is shown to induce HepG2 apoptosis in a PI3K and MAPK pathway-dependant manner.

Technology Process of MOMORDINIC

There total 2 articles about MOMORDINIC which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-O-[β-D-glucopyranosyl-(1-2)-(β-D-xylopyranosyl-(1-3))-β-D-glucuronopyranosyl]-3β-hydroxyolean-12-en-28-oic acid → (3β)-17-carboxy-28-norolean-12-en-3-yl 3'-O-(β-D-xylopyranosyl)-β-D-glucuronide (96990-18-0) + calenduloside E (26020-14-4,108322-31-2) + zingibroside R1

Guidance literature:

With sulfuric acid; at 80 ℃; for 10h;

DOI:10.1055/s-2006-958134

Reference yield:

methanol (67-56-1) + Hemsloside G1 (129385-80-4) → Methyl gentiobioside (105498-19-9) + C41H64O13 (95851-40-4,96990-18-0)

Guidance literature:

With 2,6-dimethylpyridine; lithium iodide; for 42h; Heating;

DOI:10.1248/cpb.38.1320

Reference yield:

(3β)-17-carboxy-28-norolean-12-en-3-yl 3'-O-(β-D-xylopyranosyl)-β-D-glucuronide (96990-18-0) → Oleanolic acid (508-02-1) + calenduloside E (26020-14-4,108322-31-2)

Guidance literature:

With sulfuric acid; at 80 ℃; for 10h;

DOI:10.1055/s-2006-958134

upstream raw materials:

methanol

Hemsloside G₁

Downstream raw materials:

Oleanolic acid

calenduloside E

Refernces

• 1、 Kasai,Tanaka,Nie,Miyakoshi,Zhou,Tanaka. "Saponins from Chinese medicinal plant, Hemsleya graciliflora (Cucurbitaceae)". . p. 1320 - 1322. Retrieved 2007/10/02.