2-Hydroxydodecanedioic acid

Base Information

• Chemical Name: 2-Hydroxydodecanedioic acid
• CAS No.: 74661-16-8
• Molecular Formula: C₁₂H₂₂O₅
• Molecular Weight: 246.304
• Hs Code.: 2918199090
• DSSTox Substance ID: DTXSID40996175
• Mol file: 74661-16-8.mol

Synonyms:2-hydroxydodecanedioic acid

Chemical Property of 2-Hydroxydodecanedioic acid

Chemical Property:

• Vapor Pressure: 2.88E-10mmHg at 25°C
• Boiling Point: 456.9°C at 760 mmHg
• Flash Point: 244.2°C
• PSA: 94.83000
• Density: 1.152g/cm³
• LogP: 2.02740
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 11
• Exact Mass: 246.14672380
• Heavy Atom Count: 17
• Complexity: 227

Purity/Quality:

99%min ^*data from raw suppliers

2-HydroxydodecanedioicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CCCCC(C(=O)O)O)CCCCC(=O)O
• Uses: 2-Hydroxydodecanedioic Acid can be found in urine samples from?patients with?calcium-4-(2,4-dihydroxy-3,3-dimethylbutyramido) butyrate hemihydrate (hopantenate) therapy during episodes of Reye''s-like syndrome. It is also a useful compound for developing treatments for skin disorders (psoriasis, severe dryness, itchiness, stretch marks, acne, microbial infection etc.).

Technology Process of 2-Hydroxydodecanedioic acid

There total 2 articles about 2-Hydroxydodecanedioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,12-dodecanedioic acid (693-23-2) → 2-hydroxy dodecanedioic acid (74661-16-8) + 3-hydroxydodecanedioic acid (34574-69-1)

Guidance literature:

With formate dehydrogenase; 1200 U catalase; OleT in combination with the putidaredoxin electron-transfer system CamAB; P₄₅₀ monooxygenase OleT; ammonium formate; β-nicotinamide adenine dinucleotide, disodium salt, reduced form; In dimethyl sulfoxide; at 20 ℃; for 24h; Catalytic behavior; Enzymatic reaction;

DOI:10.1002/ejoc.201600358

Reference yield:

→ 2-hydroxy dodecanedioic acid (74661-16-8)

Guidance literature:

upstream raw materials:

1,12-dodecanedioic acid

Refernces

• 1、 -. "Cosmetic compositions for reducing or preventing signs of cellulite". . . Retrieved 2008/06/13.