2-METHYL-1-HEXEN-3-YNE

Base Information

• Chemical Name: 2-METHYL-1-HEXEN-3-YNE
• CAS No.: 23056-94-2
• Molecular Formula: C7H10
• Molecular Weight: 94.1564
• Hs Code.: 29012990
• Mol file: 23056-94-2.mol

Synonyms:2-Methyl-1-hexen-3-yne

Chemical Property of 2-METHYL-1-HEXEN-3-YNE

Chemical Property:

• Vapor Pressure: 25.7mmHg at 25°C
• Refractive Index: n20/D 1.45(lit.)
• Boiling Point: 112.4°Cat760mmHg
• Flash Point: 7.9°C
• PSA: 0.00000
• Density: 0.769g/cm³
• LogP: 1.97590
• Water Solubility.: Insoluble in water.

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Methyl-1-hexen-3-yne 97% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F
• Statements: 11
• Safety Statements: 16-33

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 2-METHYL-1-HEXEN-3-YNE

There total 4 articles about 2-METHYL-1-HEXEN-3-YNE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

but-1-yne (107-00-6) + 2-bromoprop-1-ene (557-93-7) → 2-methyl-1-hexen-3-yne (23056-94-2)

Guidance literature:

With triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; In tetrahydrofuran; at 25 ℃; for 3h;

DOI:10.1039/b716678h

Reference yield:

2-methyl-3-hexyn-2-ol (5075-33-2) → 2-methyl-1-hexen-3-yne (23056-94-2)

Guidance literature:

With methanesulfonyl chloride; triethylamine; In dichloromethane; at 0 ℃; for 0.5h;

DOI:10.1021/acs.orglett.5b00671

Reference yield:

but-1-yne (107-00-6) + 2-iodopropene (4375-96-6) → 2-methyl-1-hexen-3-yne (23056-94-2)

Guidance literature:

but-1-yne; 2-iodopropene; With bis-triphenylphosphine-palladium(II) chloride; triethylamine; at 20 ℃; for 0.0833333h; Inert atmosphere;

With copper(l) iodide; Inert atmosphere;

DOI:10.1021/ol201503j

upstream raw materials:

dilithiated 3-methyl-but-1-yne

ethyl iodide

but-1-yne

2-bromoprop-1-ene

Downstream raw materials:

(S)-(+)-(3E)-3-ethyl-5-methyl-2-phenyl-hexa-3,5-dien-2-ol

3-ethyl-5-methyl-2-phenyl-hex-3-en-2-ol

Refernces

• 1、 Briones, John F.,Davies, Huw M. L.. "Silver triflate-catalyzed cyclopropenation of internal alkynes with donor-/acceptor-substituted diazo compounds". supporting information; experimental part. p. 3984 - 3987. Retrieved 2011/09/16.