2,2-diMethylbut-3-ynoyl chloride

Base Information

• Chemical Name: 2,2-diMethylbut-3-ynoyl chloride
• CAS No.: 114081-07-1
• Molecular Formula: C6H7ClO
• Molecular Weight: 130.57200
• Mol file: 114081-07-1.mol

Synonyms:2,2-Dimethyl-but-3-ynoyl chloride;

Chemical Property of 2,2-diMethylbut-3-ynoyl chloride

Chemical Property:

• Boiling Point: 132.3±23.0 °C(Predicted)
• PSA: 17.07000
• Density: 1.089±0.06 g/cm3(Predicted)
• LogP: 1.41120

Purity/Quality:

99% ^*data from raw suppliers

2,2-Dimethylbut-3-ynoylChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2-diMethylbut-3-ynoyl chloride

There total 1 articles about 2,2-diMethylbut-3-ynoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

2,2-dimethyl-3-butynoic acid (56663-76-4) → 2,2-dimethyl-but-3-ynoyl chloride (114081-07-1)

Guidance literature:

With thionyl chloride; for 4h; Heating;

DOI:10.1021/jm00010a029

Reference yield: 81.0%

N-Benzylaniline (758640-21-0,103-32-2) + 2,2-dimethyl-but-3-ynoyl chloride (114081-07-1) → N-benzyl-2,2-dimethyl-N-phenyl-3-butynamide

Guidance literature:

In diethyl ether; for 5h; Ambient temperature;

DOI:10.1002/hlca.19870700708

Reference yield: 27.0%

N-(3-pyridine)benzylamine (114081-08-2) + 2,2-dimethyl-but-3-ynoyl chloride (114081-07-1) → N-benzyl-2,2-dimethyl-N-(3-pyridyl)-3-butynamide (114081-11-7)

Guidance literature:

In diethyl ether; for 5h; Ambient temperature;

DOI:10.1002/hlca.19870700708

upstream raw materials:

2,2-dimethyl-3-butynoic acid

Downstream raw materials:

N-benzyl-2,2-dimethyl-N-(3-pyridyl)-3-butynamide

Refernces