5-fluorohistidine

Base Information

• Chemical Name: 5-fluorohistidine
• CAS No.: 57372-70-0
• Molecular Formula: C6H8FN3O2
• Molecular Weight: 173.145
• Mol file: 57372-70-0.mol

Synonyms:

Chemical Property of 5-fluorohistidine

Chemical Property:

• Vapor Pressure: 4.61E-09mmHg at 25°C
• Boiling Point: 454.8°Cat760mmHg
• Flash Point: 228.9°C
• Density: 1.529g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-fluorohistidine

There total 2 articles about 5-fluorohistidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.8%

diethyl 2-acetamido-2-((4-fluoro-1H-imidazol-5-yl)-methyl)malonate → 4-fluorohistidine (57372-70-0)

Guidance literature:

With hydrogenchloride; In water; for 8h; Reflux;

DOI:10.1039/c7ob00844a

Reference yield:

→ 4-fluorohistidine (57372-70-0)

Guidance literature:

/BRN= 840761/, saure Hydrolyse;

DOI:10.1021/ja00741a048

Refernces

• 1、 Kirk,Cohen. "Photochemical decomposition of diazonium fluoroborates. Application to the synthesis of ring-fluorinated imidazoles.". . p. 3060 - 3061. Retrieved 2007/10/09.