2-(2-Propoxyethoxy)ethanol

Base Information

• Chemical Name: 2-(2-Propoxyethoxy)ethanol
• CAS No.: 6881-94-3
• Molecular Formula: C7H16 O3
• Molecular Weight: 148.202
• Hs Code.: 2909499000
• European Community (EC) Number: 229-985-7
• UNII: T8K0B3U2HC
• DSSTox Substance ID: DTXSID1027639
• Nikkaji Number: J116.323J
• Wikidata: Q27289814
• Mol file: 6881-94-3.mol

Synonyms:2-(2-Propoxyethoxy)ethanol;6881-94-3;Ethanol, 2-(2-propoxyethoxy)-;Ethanol,2-(2-propoxyethoxy)-;propyl carbitol;Diethylene glycol monopropyl ether;UNII-T8K0B3U2HC;T8K0B3U2HC;DTXSID1027639;EINECS 229-985-7;3,6-dioxanonan-1-ol;SCHEMBL55608;2-(2-propoxyethoxy)-ethanol;Diethylene glycol propyl ether;DTXCID407639;PROPOXY DIETHYLENE GLYCOL;2-(PROPOXYETHOXY)ETHANOL;diethylene glycol ethylmethyl ether;Tox21_200097;AKOS012995735;Diethylene glycol monopropyl ether, 99%;ethanol, 2-(2-propoxyethoxy)- (DGPE);NCGC00248523-01;NCGC00257651-01;AS-77728;CAS-6881-94-3;DIETHYLENE GLYCOL MONO-N-PROPYL ETHER;D97202;Q27289814

Chemical Property of 2-(2-Propoxyethoxy)ethanol

Chemical Property:

• Vapor Pressure: 0.0292mmHg at 25°C
• Melting Point: -15.45°C (estimate)
• Refractive Index: n20/D 1.435(lit.)
• Boiling Point: 212-216 °C(lit.)
• PKA: 14.37±0.10(Predicted)
• Flash Point: 210 °F
• PSA: 38.69000
• Density: 0.969 g/mL at 25 °C(lit.)
• LogP: 0.42190
• XLogP3: 0.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 7
• Exact Mass: 148.109944368
• Heavy Atom Count: 10
• Complexity: 56.8

Purity/Quality:

98%,99%, ^*data from raw suppliers

Ethanol,2-(2-propoxyethoxy)- 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Solvents -> Glycol Ethers (E Series)
• Canonical SMILES: CCCOCCOCCO

Technology Process of 2-(2-Propoxyethoxy)ethanol

There total 3 articles about 2-(2-Propoxyethoxy)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.3%

propyl bromide (106-94-5) + diethylene glycol (111-46-6) → 2-[2-(n-propoxy)ethoxy]ethanol (6881-94-3)

Guidance literature:

With sodium hydride; In tetrahydrofuran; mineral oil; for 12h; Cooling with ice; Reflux;

Reference yield:

propyl bromide (106-94-5) → 2-[2-(n-propoxy)ethoxy]ethanol (6881-94-3)

Guidance literature:

With diethylene glycol;

DOI:10.1017/S1092852900017922

Reference yield:

→ 2-[2-(n-propoxy)ethoxy]ethanol (6881-94-3)

Guidance literature:

Ethylenoxid, n-Propanol;

upstream raw materials:

propyl bromide

diethylene glycol

Refernces

• 1、 -. "COMPOUND HAVING HIGHER INHIBITION OF PROTEIN KINASE G ACTIVITY AND PREPARATION METHOD THEREFOR". Paragraph 0134; 0135. . Retrieved 2016/12/12.