Technology Process of 1-Cholanthrenone
There total 8 articles about 1-Cholanthrenone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen fluoride;
for 15h;
Ambient temperature;
DOI:10.1021/jo00158a012
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 83 percent / zinc dust, iodine / benzene; diethyl ether / 1.) 15 min, reflux, 2.) 2h, reflux
2: 1.) p-TsOH, 2.) 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) / 1.) benzene, reflux, 2h, 2.) reflux, 4h
3: 88 percent / aq. KOH / methanol / 1 h / Heating
4: 88 percent / anhydrous HF / 15 h / Ambient temperature
With
potassium hydroxide; hydrogen fluoride; iodine; toluene-4-sulfonic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; zinc;
In
methanol; diethyl ether; benzene;
DOI:10.1021/jo00158a012
