2,4-DIAMINOBENZOIC ACID DIHYDROCHLORIDE

Base Information

• Chemical Name: 2,4-DIAMINOBENZOIC ACID DIHYDROCHLORIDE
• CAS No.: 611-03-0
• Molecular Formula: C7H8N2O2
• Molecular Weight: 152.153
• Hs Code.: 2922499990
• Mol file: 611-03-0.mol

Synonyms:Benzoic acid, 2,4-diamino-;4-Aminoanthranilic acid;4-amino-2-aminobenzoic acid;Benzoic acid,2,4-diamino;1,3-diaminobenzene-4-carboxylic acid;2,4-Diamino-benzoesaeure;2,4-diaminobenzenecarboxylic acid;2,4-diamino-benzoic acid;

Chemical Property of 2,4-DIAMINOBENZOIC ACID DIHYDROCHLORIDE

Chemical Property:

• Vapor Pressure: 3.61E-07mmHg at 25°C
• Melting Point: 140°C
• Refractive Index: 1.5200 (estimate)
• Boiling Point: 401.5°Cat760mmHg
• PKA: 5.60±0.10(Predicted)
• Flash Point: 196.7°C
• PSA: 89.34000
• Density: 1.428g/cm³
• LogP: 1.71160
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature

Purity/Quality:

98%min ^*data from raw suppliers

2,4-DiaminobenzoicAcid ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2,4-Diaminobenzoic Acid is a reagent used in the optimization of quinazolinones acting as anti-tubercular agents. Also used in the preparation of DNA Polymerase III inhibitors.

Technology Process of 2,4-DIAMINOBENZOIC ACID DIHYDROCHLORIDE

There total 9 articles about 2,4-DIAMINOBENZOIC ACID DIHYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Nitroanthranilic acid (619-17-0) → 4-amino-2-aminobenzoic acid (611-03-0)

Guidance literature:

With hydrogenchloride; tin;

Reference yield:

2,4-diacetylaminobenzoic acid (73748-78-4) → 4-amino-2-aminobenzoic acid (611-03-0)

Guidance literature:

With hydrogenchloride; ethanol;

Reference yield:

2,4-diacetylaminotoluene (6282-12-8) → 4-amino-2-aminobenzoic acid (611-03-0)

Guidance literature:

Multi-step reaction with 2 steps

1: water; calcium permanganate / 95 °C

2: alcohol; concentrated hydrochloric acid

With hydrogenchloride; calcium permanganate; ethanol; water;

upstream raw materials:

2,4-diacetylaminobenzoic acid

4-Nitroanthranilic acid

1-ethyl-2,4-dinitrobenzene

2,4-diacetylaminotoluene

Downstream raw materials:

4-Nitroanthranilic acid

C₈H₇N₃OS

2-acetylamido-4-methyl-5-nitrobenzoic acid

7-aminoquinazoline-2,4(1H,3H)-dione

Refernces

• 1、 Heppell, Jacob,Al-Rawi, Jasim. "Functionalization of quinazolin-4-ones part 1: Synthesis of novel 7-substituted-2-thioxo quinazolin-4-ones from 4-substituted-2-aminobenzoic acids and PPh3(SCN)2". . p. 162 - 174. Retrieved 2014/02/14.
• 2、 -. "One step hair coloring compositions using salts". . . Retrieved 2008/06/13.