Technology Process of 2-ethoxy-3-(icosanoylamino)propyl 2-(trimethylammonio)ethyl phosphate
There total 13 articles about 2-ethoxy-3-(icosanoylamino)propyl 2-(trimethylammonio)ethyl phosphate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
silver carbonate;
In
chloroform; water; N,N-dimethyl-formamide; isopropyl alcohol;
at 65 ℃;
for 6h;
DOI:10.1021/jm00108a021
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: p-TsOH; MeOH / CH2Cl2 / 8 h / 20 °C
2.1: pyridine / diethyl ether; tetrahydrofuran / 4 h / Heating
2.2: H2O; pyridine / diethyl ether; tetrahydrofuran / 1 h
3.1: CHCl3; propan-2-ol; various solvent(s) / 5 h / 65 °C
With
pyridine; methanol; toluene-4-sulfonic acid;
In
tetrahydrofuran; diethyl ether; dichloromethane; chloroform; isopropyl alcohol;
DOI:10.1021/jm020001x
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: pyridine / dimethylformamide / 2 h
2.1: pyridine / 10 h / 45 - 50 °C
3.1: NaH / tetrahydrofuran / 1 h / 20 °C
3.2: tetrahydrofuran / 4 h / 50 °C
4.1: p-TsOH; MeOH / CH2Cl2 / 8 h / 20 °C
5.1: pyridine / diethyl ether; tetrahydrofuran / 4 h / Heating
5.2: H2O; pyridine / diethyl ether; tetrahydrofuran / 1 h
6.1: CHCl3; propan-2-ol; various solvent(s) / 5 h / 65 °C
With
pyridine; methanol; sodium hydride; toluene-4-sulfonic acid;
In
tetrahydrofuran; diethyl ether; dichloromethane; chloroform; N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1021/jm020001x