Pioglitazone

Base Information Edit

Chemical Name:Pioglitazone
CAS No.:105355-27-9
Molecular Formula:C19H20N2O3S
Molecular Weight:356.445
Hs Code.:2934999090
Mol file:105355-27-9.mol

Synonyms:5-[[4-[2-(5-Ethylpyridin-2-yl)ethoxy]phenyl]methyl]thiazolidine-2,4-dione;

Suppliers and Price of Pioglitazone

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AHH
Pioglitazone 98%
5g
$ 710.00

Total 45 raw suppliers

Chemical Property of Pioglitazone Edit

Chemical Property:

Vapor Pressure:3.03E-13mmHg at 25°C
Melting Point:183-184oC
Boiling Point:575.4 °C at 760 mmHg
Flash Point:301.8 °C
PSA：93.59000
Density:1.26 g/cm³
LogP:3.48840

Purity/Quality:

99% ^*data from raw suppliers

Pioglitazone 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Clinical Use Treatment of type 2 diabetes mellitus
Drug interactions Potentially hazardous interactions with other drugs None known

Technology Process of Pioglitazone

There total 53 articles about Pioglitazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 136401-69-9
5-{4-[2-(5-ethyl-pyridin-2-yl)ethoxy]benzylidene}-2,4-thiazolidinedione

: 105355-27-9,111025-46-8
Pioglitazone

Guidance literature:: With hydrogen; polymer incarcerated palladium; In tetrahydrofuran; at 20 ℃; for 24h; under 760 Torr;
DOI:10.1021/jo0358527

Reference yield: 90.0%

: 105355-26-8
5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2-imino-4-thiazolidinone

: 105355-27-9,111025-46-8
Pioglitazone

Guidance literature:: With hydrogenchloride; In methanol; water; for 18h; Heating / reflux;

Reference yield: 88.0%

: 136401-70-2
(E)-5-<4-<2-(5-Ethyl-2-pyridyl)ethoxy>benzylidene>-2,4-thiazolidinedione

: 105355-27-9,111025-46-8
Pioglitazone

Guidance literature:: With sodium tetrahydroborate; butane-2,3-dione-bis-methylimine; sodium hydroxide; cobaltous chloride hexahydrate; In polyethylene glycol-400 (PEG-400); water; N,N-dimethyl-formamide; at 0 - 15 ℃;