3,4-Dimethoxybenzophenone

Base Information

• Chemical Name: 3,4-Dimethoxybenzophenone
• CAS No.: 4038-14-6
• Molecular Formula: C15H14O3
• Molecular Weight: 242.274
• Hs Code.: 2914509090
• Mol file: 4038-14-6.mol

Synonyms:Benzophenone,3,4-dimethoxy- (6CI,7CI,8CI);NSC 145888;

Chemical Property of 3,4-Dimethoxybenzophenone

Chemical Property:

• Vapor Pressure: 5.34E-06mmHg at 25°C
• Melting Point: 103-104 °C
• Refractive Index: 1.557
• Boiling Point: 380.7 °C at 760 mmHg
• Flash Point: 175.5 °C
• PSA: 35.53000
• Density: 1.123 g/cm³
• LogP: 2.93480
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

3,4-Dimethoxybenzophenone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,4-Dimethoxybenzophenone

There total 46 articles about 3,4-Dimethoxybenzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1,2-dimethoxybenzene (91-16-7) + benzoyl chloride (98-88-4) → 3,4-dimethoxybenzophenone (4038-14-6)

Guidance literature:

With bismuth(lll) trifluoromethanesulfonate; for 0.0833333h; Ionic liquid; Microwave irradiation;

DOI:10.1016/j.tetlet.2011.11.022

Reference yield: 100.0%

1,2-dimethoxybenzene (91-16-7) + benzoic acid anhydride (93-97-0) → 3,4-dimethoxybenzophenone (4038-14-6)

Guidance literature:

With silver perchlorate; niobium pentachloride; In nitromethane; at 80 ℃; for 7h;

DOI:10.1016/j.tet.2005.02.061

Reference yield: 98.0%

tert-butyl benzoyl(tert-butoxycarbonyl)carbamate (135364-97-5) + 3,4-Dimethoxyphenylboronic acid (122775-35-3) → 3,4-dimethoxybenzophenone (4038-14-6)

Guidance literature:

With (3-phenylallyl)(chloro)-[1,3-bis(2,6-diisopropylphenyl)-4,5-dihydroimidazol-2-ylidene]palladium(II); potassium carbonate; In tetrahydrofuran; water; at 23 ℃; for 15h; Inert atmosphere; Schlenk technique;

DOI:10.1021/acs.orglett.7b03191

upstream raw materials:

(+/-)-(3,4-dimethoxyphenyl)phenylmethanol

1,2-dimethoxybenzene

benzoyl chloride

benzoic acid

Downstream raw materials:

3,4-dimethoxythiobenzophenone

(+/-)-(3,4-dimethoxyphenyl)phenylmethanol

(4,5-dimethoxy-2-nitrophenyl)-(phenyl)methanone

(3,4-dimethoxyphenyl)diphenylmethanol

Refernces

• 1、 Wang, Xia,Xing, Yue,Su, Jing,Wang, Changsheng,Wang, Zishi,Yu, Yinghui,Xu, Hongliang,Ma, DongSheng. "Synthesis of two new naphthalene-containing compounds and their bindings to human serum albumin". . p. 3435 - 3448. Retrieved 2020/07/04.
• 2、 Trofimova, Alina,Holownia, Aleksandra,Tien, Chieh-Hung,?irvinskas, Martynas J.,Yudin, Andrei K.. "Acylboronates in polarity-reversed generation of acyl palladium(II) intermediates". supporting information. p. 3294 - 3299. Retrieved 2021/05/07.