Technology Process of (15R)-6,11,12,14,16-Pentahydroxyabieta-5,8,11,13-tetren-7-one
There total 7 articles about (15R)-6,11,12,14,16-Pentahydroxyabieta-5,8,11,13-tetren-7-one which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: pyridine / 1 h / 0 - 5 °C
2: 1.) zinc powder, 2.) CrO3, H2SO4 / 1.) pyridine, O deg C to 5 deg C, 1 h; 2.) acetone, 0 deg C to 5 deg C, 3 min
3: 27.4 percent / CrO3, H2SO4 / acetone / 0 deg C to 5 deg C, 5 min, RT, 2.5 h
4: 98.9 percent / 15 percent HCl / methanol / 2 h / Heating
With
pyridine; chromium(VI) oxide; hydrogenchloride; sulfuric acid; zinc;
In
methanol; acetone;
DOI:10.1246/bcsj.60.2435
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 80 percent m-chloroperbenzoic acid / methanol / 4 h / Ambient temperature
2: 5 percent HCl / methanol / 0.5 h / Heating
3: pyridine / 1 h / 0 - 5 °C
4: 1.) zinc powder, 2.) CrO3, H2SO4 / 1.) pyridine, O deg C to 5 deg C, 1 h; 2.) acetone, 0 deg C to 5 deg C, 3 min
5: 27.4 percent / CrO3, H2SO4 / acetone / 0 deg C to 5 deg C, 5 min, RT, 2.5 h
6: 98.9 percent / 15 percent HCl / methanol / 2 h / Heating
With
pyridine; chromium(VI) oxide; hydrogenchloride; sulfuric acid; 3-chloro-benzenecarboperoxoic acid; zinc;
In
methanol; acetone;
DOI:10.1246/bcsj.60.2435
