N~1~,N~1~-dimethylalaninamide(SALTDATA: 1HCl 0.01C6H4(COOH)2)

Base Information

• Chemical Name: N~1~,N~1~-dimethylalaninamide(SALTDATA: 1HCl 0.01C6H4(COOH)2)
• CAS No.: 124491-96-9
• Molecular Formula: C5H12N2O
• Molecular Weight: 116.163
• Hs Code.: 2924199090
• Mol file: 124491-96-9.mol

Synonyms:alanine dimethylamide;(+/-)-9,9'-spirobixanthene-1,1'-diol;2-aminopropionic acid N,N-(dimethyl)amide;Phoenicoxanthin;rac-9,9'-spirobixanthene-1,1'-diol;(RS)-alanine N,N-dimethylamide;DL-2-Amino-propionsaeure-dimethylamid;rac-Adinorubin;Alanin-dimethylamid;rac-alanine N,N-dimethylamide;DL-Alanin-dimethylamid;9,9'-Spirobi[9H-xanthene]-1,1'-diol;

Chemical Property of N~1~,N~1~-dimethylalaninamide(SALTDATA: 1HCl 0.01C6H4(COOH)2)

Chemical Property:

• PSA: 46.33000
• LogP: 0.92410

Purity/Quality:

98%min ^*data from raw suppliers

2-Amino-N,N-dimethylpropanamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N~1~,N~1~-dimethylalaninamide(SALTDATA: 1HCl 0.01C6H4(COOH)2)

There total 3 articles about N~1~,N~1~-dimethylalaninamide(SALTDATA: 1HCl 0.01C6H4(COOH)2) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dimethyl amine (124-40-3) + rac-Ala-OH (302-72-7,25191-17-7,18875-37-1) → (RS)-alanine N,N-dimethylamide (124491-96-9)

Guidance literature:

With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃; for 24h;

DOI:10.1039/b211914e

Reference yield:

DL-N-carbobenzoxyalanine dimethylamide (75801-52-4) → (RS)-alanine N,N-dimethylamide (124491-96-9)

Guidance literature:

With hydrogen; Yield given;

DOI:10.1021/jo00316a004

Reference yield:

dimethyl amine (124-40-3) + DL-4-methyl-1,3-oxazolidine-2,5-dione (2224-52-4,4829-14-5,30291-41-9,45530-11-8,45530-21-0) → (RS)-alanine N,N-dimethylamide (124491-96-9)

Guidance literature:

upstream raw materials:

dimethyl amine

DL-4-methyl-1,3-oxazolidine-2,5-dione

DL-N-carbobenzoxyalanine dimethylamide

rac-Ala-OH

Downstream raw materials:

potassium formate

potassium oxalate

Refernces

• 1、 Guthrie, Robert D.,Hrovat, David A.,Prahl, Fredrick G.,Swan, James. "Carbanions. Electron Transfer vs. Proton Capture. 7. Electron-Transfer Oxidation of an Amino Acid Derived Carbanion". . p. 498 - 501. Retrieved 2007/10/02.