[Z,(+)]-9-Octadecene-1,12-diol 12-acetate

Base Information

• Chemical Name: [Z,(+)]-9-Octadecene-1,12-diol 12-acetate
• CAS No.: 2581-27-3
• Molecular Formula: C₂₀H₃₈O₃
• Molecular Weight: 326.52
• Mol file: 2581-27-3.mol

Synonyms:9-Octadecene-1,12-diol,12-acetate, (Z)-(+)- (8CI); Gyplure

Chemical Property of [Z,(+)]-9-Octadecene-1,12-diol 12-acetate

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [Z,(+)]-9-Octadecene-1,12-diol 12-acetate

There total 6 articles about [Z,(+)]-9-Octadecene-1,12-diol 12-acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(9Z,12R)-octadec-9-ene-1,12-diol (540-11-4) → (+)-12-Acetoxy-trans-octadec-9-en-1-ol (2581-27-3,2581-29-5,6810-38-4,20312-23-6)

Guidance literature:

Multi-step reaction with 3 steps

1: Py / benzene

2: aq. KOH / ethanol

3: (i) aq. HNO₃, NaNO₂, (ii) aq. KOH

With pyridine; potassium hydroxide; In ethanol; benzene;

DOI:10.1021/jo01054a052

Reference yield:

Ricinoleic acid (141-22-0,27925-02-6,7431-95-0,84799-84-8) → (+)-12-Acetoxy-trans-octadec-9-en-1-ol (2581-27-3,2581-29-5,6810-38-4,20312-23-6)

Guidance literature:

Multi-step reaction with 4 steps

1: LiAlH₄

2: Py / benzene

3: aq. KOH / ethanol

4: (i) aq. HNO₃, NaNO₂, (ii) aq. KOH

With pyridine; potassium hydroxide; lithium aluminium tetrahydride; In ethanol; benzene;

DOI:10.1021/jo01054a052

Reference yield:

(R)-1,12-diacetoxy-octadec-9c-ene (95806-05-6) → (+)-12-Acetoxy-trans-octadec-9-en-1-ol (2581-27-3,2581-29-5,6810-38-4,20312-23-6)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. KOH / ethanol

2: (i) aq. HNO₃, NaNO₂, (ii) aq. KOH

With potassium hydroxide; In ethanol;

DOI:10.1021/jo01054a052

upstream raw materials:

1.12-Diacetoxy-octadecen-(9-cis)

(R)-1,12-diacetoxy-octadec-9t-ene

(9Z,12R)-octadec-9-ene-1,12-diol

Ricinoleic acid

Refernces