Technology Process of Benzenamine,
5-chloro-2-[(1H-imidazol-2-ylsulfinyl)methyl]-N-(2-methylpropyl)-
There total 5 articles about Benzenamine,
5-chloro-2-[(1H-imidazol-2-ylsulfinyl)methyl]-N-(2-methylpropyl)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
ammonium metavanadate; dihydrogen peroxide; acetic acid;
In
methanol; chloroform;
at -3 - 3 ℃;
for 2.5h;
DOI:10.1248/cpb.40.675
- Guidance literature:
-
Multi-step reaction with 5 steps
1: K2CO3 / benzene / 2 h / Heating
2: LiAlH4 / tetrahydrofuran / 1.) 0 deg C, 30 min, 2.) 50 deg C, 1 h
3: SOCl2 / CH2Cl2 / 0.5 h / 0 °C
4: ethanol / 1 h / Ambient temperature
5: 1.) AcOH, 2.) 35percent H2O2, NH4VO3 / 1.) CHCl3, MeOH, RT, 30 min, 2.) CHCl3, MeOH, from -3 deg C to 3 deg C, 2.5 h
With
ammonium metavanadate; lithium aluminium tetrahydride; thionyl chloride; dihydrogen peroxide; potassium carbonate; acetic acid;
In
tetrahydrofuran; ethanol; dichloromethane; benzene;
DOI:10.1248/cpb.40.675
- Guidance literature:
-
Multi-step reaction with 3 steps
1: SOCl2 / CH2Cl2 / 0.5 h / 0 °C
2: ethanol / 1 h / Ambient temperature
3: 1.) AcOH, 2.) 35percent H2O2, NH4VO3 / 1.) CHCl3, MeOH, RT, 30 min, 2.) CHCl3, MeOH, from -3 deg C to 3 deg C, 2.5 h
With
ammonium metavanadate; thionyl chloride; dihydrogen peroxide; acetic acid;
In
ethanol; dichloromethane;
DOI:10.1248/cpb.40.675