Phosphine, diphenyl[(tetrahydro-2H-pyran-2-yl)methyl]-

Base Information

• Chemical Name: Phosphine, diphenyl[(tetrahydro-2H-pyran-2-yl)methyl]-
• CAS No.: 135492-09-0
• Molecular Formula: C₁₈H₂₁OP
• Molecular Weight: 284.338
• Mol file: 135492-09-0.mol

Synonyms:

Chemical Property of Phosphine, diphenyl[(tetrahydro-2H-pyran-2-yl)methyl]-

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Phosphine, diphenyl[(tetrahydro-2H-pyran-2-yl)methyl]-

There total 1 articles about Phosphine, diphenyl[(tetrahydro-2H-pyran-2-yl)methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(chloromethyl)tetrahydropyran (18420-41-2,130233-13-5,130233-14-6) + diphenylphosphane (829-85-6) → Diphenyl(tetrahydropyranyl-2-methyl)phosphan (135492-09-0)

Guidance literature:

With sodium; Yield given. Multistep reaction; 1) fl. NH₃, Et₂O, 2) -50 deg C, 0.5 h;

Reference yield: 92.0%

tris(triphenylphosphine)ruthenium(II) chloride (15529-49-4,41756-81-4) + Diphenyl(tetrahydropyranyl-2-methyl)phosphan (135492-09-0) → trans-dichloro-cis-bis{diphenyl(tetrahydropyran-2-ylmethyl)phosphane-O,P}ruthenium(II) (140658-03-3)

Guidance literature:

In dichloromethane; byproducts: PPh3; Ar atmosphere; stirring (30 min, room temp.); partial evapn. (vac.),pptn. on addn. of hexane, filtration, washing (hexane), drying (vac.); elem. anal.;

Reference yield: 89.0%

cobalt(II) iodide dihydrate + Diphenyl(tetrahydropyranyl-2-methyl)phosphan (135492-09-0) → diiodo-bis{diphenyl(tetrahydropyranyl-2-methyl)phosphane-P}cobalt(II) (138270-69-6)

Guidance literature:

In methanol; isopropyl alcohol; under exclusion of air and moisture, in purified Ar; the P-compd. is dissolved in i-propanol and heated to boiling, a filtered soln. of the Co-compd. in a i-propanol/methanol mixt. (2:1) is added dropwise within 30 min, refluxing for 4 h; pptn. after cooling to room temp., washing with cold i-propanol for two times and drying in vac., elem. anal.;

upstream raw materials:

2-(chloromethyl)tetrahydropyran

diphenylphosphane

Downstream raw materials:

diiodo-bis{diphenyl(tetrahydropyranyl-2-methyl)phosphane-P}cobalt(II)

trans-dichloro-cis-bis{diphenyl(tetrahydropyran-2-ylmethyl)phosphane-O,P}ruthenium(II)

cis-dichlorobis{diphenyl(tetrahydropyranyl-2-methyl)phosphane-P}platinum(II)

cis-dichlorobis{diphenyl(tetrahydropyranyl-2-methyl)phosphane-P}palladium(II)

Refernces