(S)-N-Carbobenzyloxy-4-amino-2-hydroxybutyric acid

Base Information Edit

Chemical Name:(S)-N-Carbobenzyloxy-4-amino-2-hydroxybutyric acid
CAS No.:40371-50-4
Molecular Formula:C12H15NO5
Molecular Weight:253.255
Hs Code.:29242990
European Community (EC) Number:254-892-3
DSSTox Substance ID:DTXSID401177349
Nikkaji Number:J24.916E
Wikidata:Q76146092
ChEMBL ID:CHEMBL459549
Mol file:40371-50-4.mol

Synonyms:40371-50-4;(S)-N-Carbobenzyloxy-4-amino-2-hydroxybutyric acid;(S)-N-CBZ-4-amino-2-hydroxybutyric acid;Cbz-HABA;(S)-(+)-Z-4-Amino-2-hydroxybutyric acid;(2S)-2-hydroxy-4-(phenylmethoxycarbonylamino)butanoic acid;EINECS 254-892-3;(S)-(+)-N-Carboxybenzoyl-4-Amino-2-hydroxybutyric Acid;(S)-4-(((benzyloxy)carbonyl)amino)-2-hydroxybutanoic acid;(S)-2-Hydroxy-4-(((phenylmethoxy)carbonyl)amino)butyric acid;(S)-4-(benzyloxycarbonylamino)-2-hydroxybutanoic acid;(S)-2-Hydroxy-4-[[(phenylmethoxy)carbonyl]amino]butyric acid;ACIDOL-4BENZYLOXYCARBONYL-AMINO-2HYDROXY BUTYRIC;S,4-benzyloxycarbonylamino-2-hyroxybutyric acid;SCHEMBL334926;CHEMBL459549;ULKOBRDRCYROKY-JTQLQIEISA-N;DTXSID401177349;Butanoic acid, 2-hydroxy-4-[[(phenylmethoxy)carbonyl]amino]-, (2S)-;MFCD00209957;AKOS015892555;(S)-N-CBZ-4-amino-2-hydroxybutyricacid;AS-10804;CS-0059147;EN300-6747320;(s)-4-benzyloxycarbonylamino-2-hydroxybutyric acid;4-benzyloxycarbonylamino-2(S)-hydroxybutyric acid;(2S)-4-Benzyloxycarbonylamino-2-hydroxybutyric acid;(S)-(+)-Z-4-Amino-2-hydroxybutyric acid, 97%;W-106357;(2S)-4-{[(benzyloxy)carbonyl]amino}-2-hydroxybutanoic acid;(2S)-2-Hydroxy-4-[[(phenylmethoxy)carbonyl]amino]butanoic acid;Butanoic acid, 2-hydroxy-4-[[(phenylmethoxy)carbonyl]amino]-, (S)-

Suppliers and Price of (S)-N-Carbobenzyloxy-4-amino-2-hydroxybutyric acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-(+)-N-Carboxybenzoyl-4-Amino-2-hydroxybutyricAcid
10g
$ 100.00

TRC
(S)-(+)-N-Carboxybenzoyl-4-Amino-2-hydroxybutyricAcid
25g
$ 150.00

TRC
(S)-(+)-N-Carboxybenzoyl-4-Amino-2-hydroxybutyricAcid
100g
$ 450.00

Medical Isotopes, Inc.
(S)-(+)-N-Carboxybenzoyl-4-Amino-2-hydroxybutyricAcid
25 g
$ 650.00

Frontier Specialty Chemicals
(S)-N-Carbobenzyloxy-4-amino-2-hydroxybutyricacid 96%
25g
$ 247.00

Frontier Specialty Chemicals
(S)-N-Carbobenzyloxy-4-amino-2-hydroxybutyricacid 96%
5g
$ 62.00

Crysdot
(S)-N-Cbz-4-Amino-2-hydroxybutyricacid 97%
100g
$ 492.00

Chemenu
(2S)-2-hydroxy-4-(phenylmethoxycarbonylamino)butanoicacid 95%
1000g
$ 1104.00

Biosynth Carbosynth
(S)-N-Carbobenzyloxy-4-amino-2-hydroxybutyric acid
25 g
$ 335.00

Biosynth Carbosynth
(S)-N-Carbobenzyloxy-4-amino-2-hydroxybutyric acid
50 g
$ 620.00

Total 84 raw suppliers

Chemical Property of (S)-N-Carbobenzyloxy-4-amino-2-hydroxybutyric acid Edit

Chemical Property:

Appearance/Colour:off-white crystalline powder
Vapor Pressure:1.08E-11mmHg at 25°C
Melting Point:72-78 ºC
Refractive Index:1.563
Boiling Point:521.2 ºC at 760 mmHg
PKA:3.73±0.10(Predicted)
Flash Point:269 ºC
PSA：95.86000
Density:1.311 g/cm³
LogP:1.13930
Storage Temp.:Sealed in dry,Room Temperature
Solubility.:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
XLogP3:0.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:253.09502258
Heavy Atom Count:18
Complexity:276

Purity/Quality:

99% ^*data from raw suppliers

(S)-(+)-N-Carboxybenzoyl-4-Amino-2-hydroxybutyricAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC(=O)NCCC(C(=O)O)O
Isomeric SMILES:C1=CC=C(C=C1)COC(=O)NCC[C@@H](C(=O)O)O
Uses (S)-(+)-Z-4-Amino-2-hydroxybutyric Acid is used in the synthesis of aminoglycoside antibiotics.

Technology Process of (S)-N-Carbobenzyloxy-4-amino-2-hydroxybutyric acid

There total 5 articles about (S)-N-Carbobenzyloxy-4-amino-2-hydroxybutyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: sodium 4-benzyloxycarbonylamino-2-oxobutanoate

: 40371-50-4
S-4-benzyloxycarbonylamino-2-hydroxybutyric acid

Guidance literature:: With 1,4-dihydronicotinamide adenine dinucleotide; tris buffer pH 6.5-7.0; sodium formate; diothiothreitol; for 40h; Ambient temperature; lactate dehydrogenase from Bacillus stearothermophilus, formate dehydrogenase;
DOI:10.1039/c39950000231