3-Phosphoglyceraldehyde

Base Information

• Chemical Name: 3-Phosphoglyceraldehyde
• CAS No.: 591-59-3
• Deprecated CAS: 142-10-9,1866-60-0,91469-44-2
• Molecular Formula: C₃H₇O₆P
• Molecular Weight: 170.059
• European Community (EC) Number: 209-721-7
• UNII: 7466PL1110
• DSSTox Substance ID: DTXSID40861814
• Nikkaji Number: J228.059K
• Wikipedia: Glyceraldehyde_3-phosphate
• Wikidata: Q794810
• Mol file: 591-59-3.mol

Synonyms:3 Phosphoglyceraldehyde;3-Phosphoglyceraldehyde;Glyceraldehyde 3 Phosphate;Glyceraldehyde 3-Phosphate

Chemical Property of 3-Phosphoglyceraldehyde

Chemical Property:

• Boiling Point: 399.227 °C at 760 mmHg
• PKA: 1.80±0.10(Predicted)
• Flash Point: 195.246 °C
• PSA: 113.87000
• Density: 1.722 g/cm³
• LogP: -1.34450
• Storage Temp.: −20°C
• XLogP3: -2.7
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 4
• Exact Mass: 169.99802494
• Heavy Atom Count: 10
• Complexity: 149

Purity/Quality:

98%,99%, ^*data from raw suppliers

DL-Glyceraldehyde-3-phosphate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-27-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(C=O)O)OP(=O)(O)O
• Description: DL-Glyceraldehyde-3-phosphate (GADP) is an intermediate in several metabolic pathways, including glycolysis and gluconeogenesis. In glycolysis, it can be derived from fructose 1,6-bisphosphate by fructose bisphosphate aldolase in a reaction that also produces dihydroxyacetone phosphate (DHAP). Triose phosphate isomerase reversibly converts DHAP to GADP. GADP is processed to 1,3-bisphosphoglycerate by glyceraldehyde phosphate dehydrogenase and NAD+.
• Uses: The level of Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) activity in HEK 293 cells was aβeβed by measuring the reduction of NAD+ by DL-Glyceraldehyde 3-phosphate.

Technology Process of 3-Phosphoglyceraldehyde

There total 15 articles about 3-Phosphoglyceraldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ DL-glyceraldehyde 3-phosphate (142-10-9,591-57-1,20283-52-7,591-59-3)

Guidance literature:

With hydrogenchloride; at 100 ℃;

Reference yield:

dihydroxyacetone phosphate (57-04-5) → DL-glyceraldehyde 3-phosphate (142-10-9,591-57-1,20283-52-7,591-59-3)

Guidance literature:

With potassium arsenate; NAD⁺-dependent glyceraldehyde-3-phosphate dehydrogenase; rabbit muscle triose phosphate isomerase; NAD; In triethylamine; at 37 ℃; pH=7.6; Reagent/catalyst; Enzymatic reaction;

DOI:10.1021/acs.biochem.5b00991

Reference yield:

→ DL-glyceraldehyde 3-phosphate (142-10-9,591-57-1,20283-52-7,591-59-3)

Guidance literature:

With 1,4-dioxane; water; calcium acetate; das Calciumsalz entsteht;

upstream raw materials:

lysophosphatidic acid

phosphoric acid mono-(2,3-dihydroxy-3-indol-3-yl-propyl ester)

D-arabinose-5-phosphate

dihydroxyacetone 3-phosphate dilithium salt

Downstream raw materials:

2-deoxy-D-ribose 5-phosphate

Pyridine-2,3-dicarboxylic acid

xylulose 5-phosphate

1-arseno-3-phosphoglycerate

Refernces

• 1、 Fernández-García,Grefenstette,Powner. "Prebiotic synthesis of aminooxazoline-5′-phosphates in water by oxidative phosphorylation". supporting information. p. 4919 - 4921. Retrieved 2017/07/11.
• 2、 Zhai, Xiang,Amyes, Tina L.,Wierenga, Rik K.,Loria, J. Patrick,Richard, John P.. "Structural mutations that probe the interactions between the catalytic and dianion activation sites of triosephosphate isomerase". . p. 5928 - 5940. Retrieved 2013/09/23.