Technology Process of Benzenedecanal, 3,5-dimethoxy-
There total 13 articles about Benzenedecanal, 3,5-dimethoxy- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
phosgene; dimethyl sulfoxide; triethylamine;
In
dichloromethane;
at -78 ℃;
DOI:10.1021/jm501846y
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) O3, 2.) Et3N / 1.) CH2Cl2, -78 deg C, 2.) CH2Cl2, from -78 deg C to RT
2: 1.) n-BuLi / 1.) THF, hexane, RT, 15 min, 2.) THF, hexane, RT, 18 h
3: 91 percent / H2 / 10percent Pd/C / ethanol / 12 h
4: 94 percent / p-toluenesulfonic acid, H2O / tetrahydrofuran / 18 h / Ambient temperature
5: 1.) (COCl)2, DMSO, 2.) Et3N / 1.) CH2Cl2, -78 deg C, 1 h, 2.) CH2Cl2, 0 deg C, 20 min
With
n-butyllithium; oxalyl dichloride; water; hydrogen; toluene-4-sulfonic acid; ozone; dimethyl sulfoxide; triethylamine;
palladium on activated charcoal;
In
tetrahydrofuran; ethanol;
DOI:10.1248/cpb.41.561
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) n-BuLi / 1.) THF, hexane, RT, 15 min, 2.) THF, hexane, RT, 18 h
2: 91 percent / H2 / 10percent Pd/C / ethanol / 12 h
3: 94 percent / p-toluenesulfonic acid, H2O / tetrahydrofuran / 18 h / Ambient temperature
4: 1.) (COCl)2, DMSO, 2.) Et3N / 1.) CH2Cl2, -78 deg C, 1 h, 2.) CH2Cl2, 0 deg C, 20 min
With
n-butyllithium; oxalyl dichloride; water; hydrogen; toluene-4-sulfonic acid; dimethyl sulfoxide; triethylamine;
palladium on activated charcoal;
In
tetrahydrofuran; ethanol;
DOI:10.1248/cpb.41.561