(1-AMINOPROPYL)PHOSPHONIC ACID

Base Information

• Chemical Name: (1-AMINOPROPYL)PHOSPHONIC ACID
• CAS No.: 14047-23-5
• Molecular Formula: C3H10 N O3 P
• Molecular Weight: 139.09
• Hs Code.: 2931900090
• Mol file: 14047-23-5.mol

Synonyms:Phosphonicacid, (1-aminopropyl)- (8CI,9CI); (1-Aminopropyl)phosphonic acid;1-Aminopropanephosphonic acid; AMPP; APPA; Ampropylfos; NSC 133879; PNL 62; a-Aminopropanephosphonic acid

Chemical Property of (1-AMINOPROPYL)PHOSPHONIC ACID

Chemical Property:

• Vapor Pressure: 0.00012mmHg at 25°C
• Melting Point: 263-268 °C
• Boiling Point: 311.9°Cat760mmHg
• PKA: 0.92±0.10(Predicted)
• Flash Point: 142.4°C
• PSA: 93.36000
• Density: 1.373g/cm³
• LogP: 0.55920

Purity/Quality:

99% ^*data from raw suppliers

(1-AMINOPROPYL)PHOSPHONIC ACID AldrichCPR ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi,C
• Statements: 36/37/38-34
• Safety Statements: 37/39-26-45-36/37/39-27-22

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (1-AMINOPROPYL)PHOSPHONIC ACID

There total 26 articles about (1-AMINOPROPYL)PHOSPHONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1-Aminopropylphosphonsaeure-diethylester (18108-00-4) → 1-aminopropanephosphonic acid (14047-23-5)

Guidance literature:

With methyloxirane; In ethanol;

DOI:10.1016/0040-4039(95)02171-X

Reference yield: 87.0%

(1-Amino-propyl)-phosphonic acid; hydrobromide → 1-aminopropanephosphonic acid (14047-23-5)

Guidance literature:

With epichlorohydrin;

Reference yield: 60.4%

triphenyl phosphite (101-02-0) + propionaldehyde (123-38-6) + urethane (51-79-6) → 1-aminopropanephosphonic acid (14047-23-5)

Guidance literature:

With hydrogenchloride; acetic acid; methyloxirane; In methanol;

upstream raw materials:

1-Aminopropylphosphonsaeure-diethylester

ethylmagnesium iodide

(diethoxyphosphoryl-ethylsulfanyl-methylene)-carbamic acid ethyl ester

triethyl 2-ethylphosphonoacetate

Downstream raw materials:

1-N-Benzoylamino-propylphosphonsaeure

Refernces

• 1、 Mao, Liu-Liang,Li, Chen-Chen,Yang, Qiang,Cheng, Ming-Xing,Yang, Shang-Dong. "One-pot synthesis of α-aminophosphonates via a cascade sequence of allylamine isomerization/hydrophosphonylation". . p. 4473 - 4476. Retrieved 2017.
• 2、 Qian, Renzhe,Horak, Jeannie,Hammerschmidt, Friedrich. "Conversion of nitriles to 1-aminophosphonic acids and preparation of phosphahomocysteines of high enantiomeric excess". . p. 737 - 744. Retrieved 2017/06/05.
• 3、 -. "3-phenyl-pyrones". . . Retrieved 2008/06/13.