2-(2-[2-(2-AMINOPHENOXY)ETHOXY]ETHOXY)ANILINE

Base Information

• Chemical Name: 2-(2-[2-(2-AMINOPHENOXY)ETHOXY]ETHOXY)ANILINE
• CAS No.: 7249-78-7
• Molecular Formula: C16H20N2O3
• Molecular Weight: 288.346
• Mol file: 7249-78-7.mol

Synonyms:

Chemical Property of 2-(2-[2-(2-AMINOPHENOXY)ETHOXY]ETHOXY)ANILINE

Chemical Property:

• Vapor Pressure: 6.69E-10mmHg at 25°C
• Melting Point: 65-66 °C
• Boiling Point: 494°Cat760mmHg
• PKA: 4.59±0.10(Predicted)
• Flash Point: 275.9°C
• PSA: 79.73000
• Density: 1.19g/cm³
• LogP: 3.48780

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(2-[2-(2-AMINOPHENOXY)ETHOXY]ETHOXY)ANILINE

There total 13 articles about 2-(2-[2-(2-AMINOPHENOXY)ETHOXY]ETHOXY)ANILINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1,5-bis(o-nitrophenoxy)-3-oxapentane (54533-65-2) → 1,5-bis-(2-aminophenoxy)-3-oxapentane (7249-78-7)

Guidance literature:

With hydrogen; palladium on activated charcoal;

DOI:10.1016/S0040-4020(03)00618-5

Reference yield: 81.0%

bis-[2-(2-acetylamino-phenoxy)-ethyl] ether (73776-05-3) → 1,5-bis-(2-aminophenoxy)-3-oxapentane (7249-78-7)

Guidance literature:

With sodium hydroxide; In ethanol; water; at 80 ℃;

DOI:10.1002/ejoc.201001312

Reference yield:

2-hydroxynitrobenzene (88-75-5,78813-12-4) → 1,5-bis-(2-aminophenoxy)-3-oxapentane (7249-78-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / K₂CO₃ (calcined) / dimethylsulfoxide / 6 h / 130 °C

2: 93 percent / 85percent NH₂NH₂*H₂O / 5percent Pd/C / ethanol / 2 h / Heating

With potassium carbonate; hydrazine hydrate; palladium on activated charcoal; In ethanol; dimethyl sulfoxide;

DOI:10.1007/BF00475582

upstream raw materials:

1,5-bis(o-nitrophenoxy)-3-oxapentane

3-oxa-1,5-dichloropentane

2-amino-phenol

2-hydroxynitrobenzene

Downstream raw materials:

C₅₂H₄₆N₂O₃P₂

Refernces

• 1、 -. "Fluorescent ion indicators for cadmium and lanthanide ion detection". Page/Page column 37. . Retrieved 2014/01/07.
• 2、 Pazik, Agnieszka,Skwierawska, Anna. "Synthesis and spectroscopic properties of new bis-tetrazoles". . p. 83 - 94. Retrieved 2014/01/06.