2-HYDRAZINOQUINOXALINE

Base Information

• Chemical Name: 2-HYDRAZINOQUINOXALINE
• CAS No.: 61645-34-9
• Molecular Formula: C8H8N4
• Molecular Weight: 160.178
• Hs Code.: 29339900
• Mol file: 61645-34-9.mol

Synonyms:2(1H)-Quinoxalinone,hydrazone (9CI);Quinoxaline, 2-hydrazino- (6CI,7CI);2-Hydrazinoquinoxaline;NSC 152179;(Quinoxalin-2-yl)hydrazine;

Chemical Property of 2-HYDRAZINOQUINOXALINE

Chemical Property:

• Vapor Pressure: 2.79E-06mmHg at 25°C
• Melting Point: 170-172 °C
• Refractive Index: 1.777
• Boiling Point: 389.7 °C at 760 mmHg
• PKA: 1.30±0.20(Predicted)
• Flash Point: 189.5 °C
• PSA: 63.83000
• Density: 1.373 g/cm³
• LogP: 1.68870

Purity/Quality:

98%min ^*data from raw suppliers

2-Hydrazinoquinoxaline ^*data from reagent suppliers

Safty Information:

• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39-22

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-HYDRAZINOQUINOXALINE

There total 5 articles about 2-HYDRAZINOQUINOXALINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

2-chloroquinoxaline (1448-87-9) → 2-hydrazinoquinoxaline (61645-34-9)

Guidance literature:

With hydrazine hydrate; In ethanol; for 1h; Heating;

Reference yield:

quinoxalin-2(1)-one (1196-57-2) → 2-hydrazinoquinoxaline (61645-34-9)

Guidance literature:

Multi-step reaction with 2 steps

1: phosphoryl chloride / 1.5 h / Heating

2: 87 percent / hydrazine hydrate / ethanol / 1 h / Heating

With hydrazine hydrate; trichlorophosphate; In ethanol;

Reference yield:

1,2-diamino-benzene (95-54-5) → 2-hydrazinoquinoxaline (61645-34-9)

Guidance literature:

Multi-step reaction with 3 steps

1: ethanol

2: POCl₃

3: N₂H₄+H₂O

With ethanol; hydrazine hydrate; trichlorophosphate;

upstream raw materials:

2-chloroquinoxaline

quinoxaline-2(1H)-thione

quinoxalin-2⁽¹⁾-one

1,2-diamino-benzene

Downstream raw materials:

2-chloroquinoxaline

2-hydroxyquinoxaline

Refernces

• 1、 Chen, Chan-Yu,Lin, Tzu-Pin,Chen, Chine-Kun,Lin, Su-Ching,Tseng, Mei-Chun,Wen, Yuh-Sheng,Sun, Shih-Sheng. "New chromogenic and fluorescent probes for anion detection: Formation of a [2 + 2] supramolecular complex on addition of fluoride with positive homotropic cooperativity". . p. 900 - 911. Retrieved 2008.
• 2、 Liu, Lingfeng,Qiao, Chunhua,Shen, Bei,Xu, Yiwen. "Metal free [4+1] and [5+1] annulation reactions to prepare heterocycles using DMF and its derivatives as one-carbon source". supporting information. . Retrieved 2020/04/01.