Decanamide, 2-hydroxy-N-phenyl-

Base Information

• Chemical Name: Decanamide, 2-hydroxy-N-phenyl-
• CAS No.: 141329-99-9
• Molecular Formula: C₁₆H₂₅NO₂
• Molecular Weight: 263.38
• Mol file: 141329-99-9.mol

Synonyms:

Chemical Property of Decanamide, 2-hydroxy-N-phenyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Decanamide, 2-hydroxy-N-phenyl-

There total 4 articles about Decanamide, 2-hydroxy-N-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Trimethylsilanyloxy-decanoic acid phenylamide → N-phenyl-2-hydroxy-decanamide (141329-99-9)

Guidance literature:

With citric acid; In methanol; for 0.5h; Yield given;

DOI:10.1080/00397919208020850

Reference yield:

DL-2-hydroxydecanoic acid (5393-81-7,37639-46-6) → N-phenyl-2-hydroxy-decanamide (141329-99-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) DMAP, pyridine, 2.) oxalyl chloride, DMF / 1.) CH₂Cl₂, RT, 4 h, 2.) CH₂Cl₂, a.) 0 deg C, 1 h, b.) RT, 30 min

2: pyridine / CH₂Cl₂ / 2 h / Ambient temperature

3: citric acid / methanol / 0.5 h

With pyridine; dmap; oxalyl dichloride; N,N-dimethyl-formamide; citric acid; In methanol; dichloromethane;

DOI:10.1080/00397919208020850

Reference yield:

2-Trimethylsilanyloxy-decanoyl chloride (1035795-79-9) → N-phenyl-2-hydroxy-decanamide (141329-99-9)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / CH₂Cl₂ / 2 h / Ambient temperature

2: citric acid / methanol / 0.5 h

With pyridine; citric acid; In methanol; dichloromethane;

DOI:10.1080/00397919208020850

upstream raw materials:

DL-2-hydroxydecanoic acid

aniline

2-Trimethylsilanyloxy-decanoyl chloride

Refernces