2-Methylpropanimidamide hydrochloride

Base Information

• Chemical Name: 2-Methylpropanimidamide hydrochloride
• CAS No.: 22007-68-7
• Molecular Formula: C4H10 N2 . Cl H
• Molecular Weight: 122.598
• Hs Code.: 2925290090
• European Community (EC) Number: 639-430-4
• NSC Number: 66913
• DSSTox Substance ID: DTXSID30381915
• Mol file: 22007-68-7.mol

Synonyms:22007-68-7;2-methylpropanimidamide hydrochloride;Isobutyrimidamide hydrochloride;isobutyramidine hydrochloride;MFCD00173787;2-Methylpropanimidamide, HCl;2-methylpropanimidamide;hydrochloride;Isopropylcarbamidine hydrochloride;2-Methylpropanamidine hydrochloride;2-METHYLPROPANIMIDAMIDE HCL;Isobutanimidamide Hydrochloride;2-methylpropanimidamide chloride;Isobutyramidine HCl;2-methylpropionamidine hydrochloride;Isobutanimidamide HCl;2-methyl propanimidamide hydrochloride;Propanimidamide, 2-methyl-, monohydrochloride;isobutanamidine hydrochloride;Isobutyrimidamidehydrochloride;2-amidinopropane hydrochloride;SCHEMBL183696;DTXSID30381915;VWXLCWNPSOUPPE-UHFFFAOYSA-N;BCP07536;NSC66913;NSC-66913;Isopropanecarboximidamide hydrochloride;AKOS008105041;2-Methylpropionamidine monohydrochloride;AS-19911;SY024838;CS-0120122;FT-0613073;EN300-36994;2-methylpropanimidamide hydrochloride, AldrichCPR;J-014417;F8889-9247;Z381357616

Chemical Property of 2-Methylpropanimidamide hydrochloride

Chemical Property:

• Vapor Pressure: 25.5mmHg at 25°C
• Melting Point: 159 °C
• Boiling Point: 108.8°Cat760mmHg
• Flash Point: 19.6°C
• PSA: 49.87000
• Density: 0.97g/cm³
• LogP: 2.18040
• Storage Temp.: Inert atmosphere,Room Temperature
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 122.0610761
• Heavy Atom Count: 7
• Complexity: 56.6

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Methylpropanimidamide hydrochloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38-36
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)C(=N)N.Cl
• Uses: 2-Methylpropanamidine hydrochloride is a useful reagent for organic reactions.

Technology Process of 2-Methylpropanimidamide hydrochloride

There total 4 articles about 2-Methylpropanimidamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

Isobutyronitrile (78-82-0) → 2-methylpropanimidamide hydrochloride (22007-68-7)

Guidance literature:

Isobutyronitrile; With hydrogenchloride; In methanol; diethyl ether; at 0 ℃; for 2h;

With ammonia; In methanol; at 20 ℃;

DOI:10.1039/c4cc02346c

Reference yield:

ethyl isobutyrimidate hydrochloride (52070-18-5) → 2-methylpropanimidamide hydrochloride (22007-68-7)

Guidance literature:

With ammonia; In ethanol; for 5h; Green chemistry;

DOI:10.1071/CH14073

Reference yield:

Isobutyronitrile (78-82-0) + sodium amide → 2-methylpropanimidamide hydrochloride (22007-68-7)

Guidance literature:

unter Kuehlung und folgenden Schuetteln mit verd.HCl;

upstream raw materials:

Isobutyronitrile

ethyl isobutyrimidate hydrochloride

Downstream raw materials:

2-Isopropyl-6-methyl-4(3H)-pyrimidone

6-benzyl-2-isopropyl-3,5,6,7-tetrahydro-pyrrolo[3,4-d]pyrimidin-4-one

2-isopropyl-4-(1-methyl-1-(3-nitrophenyl)ethyl)-1H-imidazole

4,6-Dihydroxy-2-isopropyl-pyrimidin

Refernces

• 1、 Draghici, Bogdan,Vullo, Daniela,Akocak, Suleyman,Walker, Ellen A.,Supuran, Claudiu T.,Ilies, Marc A.. "Ethylene bis-imidazoles are highly potent and selective activators for isozymes VA and VII of carbonic anhydrase, with a potential nootropic effect". . p. 5980 - 5983. Retrieved 2014/05/20.