4-Chloro-7-(trifluoromethyl)quinoline

Base Information Edit

Chemical Name:4-Chloro-7-(trifluoromethyl)quinoline
CAS No.:346-55-4
Molecular Formula:C10H5ClF3N
Molecular Weight:231.605
Hs Code.:2933499090
European Community (EC) Number:206-471-0
NSC Number:91883
DSSTox Substance ID:DTXSID00188170
Nikkaji Number:J193.802I
Wikidata:Q72460499
ChEMBL ID:CHEMBL567057
Mol file:346-55-4.mol

Synonyms:4-Chloro-7-(trifluoromethyl)quinoline;346-55-4;4-chloro-7-trifluoromethylquinoline;Quinoline, 4-chloro-7-(trifluoromethyl)-;C10H5ClF3N;EINECS 206-471-0;4-chloro-7-trifluoromethyl quinoline;MFCD00006775;NSC91883;TimTec1_005248;SCHEMBL317413;CHEMBL567057;DTXSID00188170;HMS1548O12;7-trifluoromethyl-4-chloroquinoline;AMY18109;BCP32445;4-Chloro-7-trifluoromethyl-quinoline;BBL027608;GEO-00824;NSC 91883;NSC-91883;STK946268;AKOS002671341;CS-W001856;GS-6796;SB71497;4-chloro-7-(trifluoromethyl) quinoline;4-chloro-7-(trifluoromethyl)-quinoline;4-chloranyl-7-(trifluoromethyl)quinoline;BP-12401;4-Chloro-7-(trifluoromethyl)quinoline, 98%;FT-0618141;EN300-115631;A822333;W-200317;Z1492205960

Suppliers and Price of 4-Chloro-7-(trifluoromethyl)quinoline

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Chloro-7-(trifluoromethyl)quinoline
1g
$ 45.00

SynQuest Laboratories
4-Chloro-7-(trifluoromethyl)quinoline 98%
5 g
$ 68.00

SynQuest Laboratories
4-Chloro-7-(trifluoromethyl)quinoline 98%
1 g
$ 21.00

Sigma-Aldrich
4-Chloro-7-(trifluoromethyl)quinoline 98%
25g
$ 565.00

Sigma-Aldrich
4-Chloro-7-(trifluoromethyl)quinoline 98%
5g
$ 162.00

Medical Isotopes, Inc.
4-Chloro-7-(trifluoromethyl)quinoline
5 g
$ 385.00

Matrix Scientific
4-Chloro-7-(trifluoromethyl)quinoline 97%
5g
$ 56.00

Matrix Scientific
4-Chloro-7-(trifluoromethyl)quinoline 97%
1g
$ 18.00

Matrix Scientific
4-Chloro-7-(trifluoromethyl)quinoline 97%
25g
$ 237.00

Labseeker
4-CHLORO-7-(TRIFLUOROMETHYL)QUINOLINE 98
25g
$ 495.00

Total 58 raw suppliers

Chemical Property of 4-Chloro-7-(trifluoromethyl)quinoline Edit

Chemical Property:

Appearance/Colour:white to light yellow crystal powder
Vapor Pressure:7.2E-08mmHg at 25°C
Melting Point:69-71 °C(lit.)
Refractive Index:1.487
Boiling Point:265.51 °C at 760 mmHg
PKA:1.18±0.27(Predicted)
Flash Point:114.377 °C
PSA：12.89000
Density:1.428 g/cm³
LogP:3.90700
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Solubility.:chloroform: soluble25mg/mL, clear, colorless
XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:231.0062613
Heavy Atom Count:15
Complexity:231

Purity/Quality:

98% HPLC ^*data from raw suppliers

4-Chloro-7-(trifluoromethyl)quinoline ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn, Xi
Hazard Codes:Xi,Xn
Statements: 36/37/38-20/21/22
Safety Statements: 26-37/39-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=CN=C2C=C1C(F)(F)F)Cl
Uses 4-Chloro-7-(trifluoromethyl)quinoline is a reagent in the preparation of piperazinylquinolines as breast cancer inhibitors.

Technology Process of 4-Chloro-7-(trifluoromethyl)quinoline

There total 14 articles about 4-Chloro-7-(trifluoromethyl)quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%