1,2-Benzenediamine, N,N,N',N'-tetrakis(2-pyridinylmethyl)-

Base Information

• Chemical Name: 1,2-Benzenediamine, N,N,N',N'-tetrakis(2-pyridinylmethyl)-
• CAS No.: 142991-50-2
• Molecular Formula: C30H28N6
• Molecular Weight: 472.593
• Mol file: 142991-50-2.mol

Synonyms:

Chemical Property of 1,2-Benzenediamine, N,N,N',N'-tetrakis(2-pyridinylmethyl)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-Benzenediamine, N,N,N',N'-tetrakis(2-pyridinylmethyl)-

There total 10 articles about 1,2-Benzenediamine, N,N,N',N'-tetrakis(2-pyridinylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

2-chloromethylpyridine hydrochloride (6959-47-3) + 1,2-diamino-benzene (95-54-5) → N,N,N',N'-tetrakis(2-pyridylmethyl)-1,2-phenylenediamine (142991-50-2)

Guidance literature:

With potassium carbonate; potassium iodide; at 50 ℃; Inert atmosphere;

DOI:10.1039/c8dt02228c

Reference yield:

2-chloromethylpyridine (4377-33-7) → N,N,N',N'-tetrakis(2-pyridylmethyl)-1,2-phenylenediamine (142991-50-2)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium hydride / tetrahydrofuran / 60 °C / Glovebox; Schlenk technique; Inert atmosphere

2: potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / 1,4-dioxane / 90 °C / Inert atmosphere

3: water / [D₃]acetonitrile / 25 °C

With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; water; potassium acetate; sodium hydride; In tetrahydrofuran; 1,4-dioxane; [D₃]acetonitrile;

DOI:10.1016/j.poly.2020.114377

Reference yield:

2-chloromethylpyridine (4377-33-7) → C30H28N6O + N,N,N',N'-tetrakis(2-pyridylmethyl)-1,2-phenylenediamine (142991-50-2)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium hydride / tetrahydrofuran / 60 °C / Glovebox; Schlenk technique; Inert atmosphere

2: potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / 1,4-dioxane / 90 °C / Inert atmosphere

3: dihydrogen peroxide / [D₃]acetonitrile

With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; dihydrogen peroxide; potassium acetate; sodium hydride; In tetrahydrofuran; 1,4-dioxane; [D₃]acetonitrile;

DOI:10.1016/j.poly.2020.114377

upstream raw materials:

2-chloromethylpyridine hydrochloride

1,2-diamino-benzene

4-Bromo-benzene-1,2-diamine

2-chloromethylpyridine

Refernces

• 1、 Wu, Hao,Zhang, Xiaoxia,Yin, Xiangbiao,Inaba, Yusuke,Miki, Harigai,Takeshita, Kenji. "Selective separation of cadmium(II) from zinc(II) by a novel hydrophobic ionic liquid including an N,N,N′,N′-tetrakis(2-methylpyridyl)-1,2-phenylenediamine-4-amido structure: a hard-soft donor combined method". . p. 10063 - 10070. Retrieved 2018.