Acetamide, N-[5-(4-nitrophenyl)-4-[5-[(3,4,5,6-tetrahydro-2H-azepin-7-yl)amino]pent yl]-2-thiazolyl]-, monohydrobromide

Base Information

• Chemical Name: Acetamide, N-[5-(4-nitrophenyl)-4-[5-[(3,4,5,6-tetrahydro-2H-azepin-7-yl)amino]pent yl]-2-thiazolyl]-, monohydrobromide
• CAS No.: 143602-38-4
• Molecular Formula: BrH*C₂₂H₂₉N₅O₃S
• Molecular Weight: 524.482
• Mol file: 143602-38-4.mol

Synonyms:

Chemical Property of Acetamide, N-[5-(4-nitrophenyl)-4-[5-[(3,4,5,6-tetrahydro-2H-azepin-7-yl)amino]pent yl]-2-thiazolyl]-, monohydrobromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Acetamide, N-[5-(4-nitrophenyl)-4-[5-[(3,4,5,6-tetrahydro-2H-azepin-7-yl)amino]pent yl]-2-thiazolyl]-, monohydrobromide

There total 2 articles about Acetamide, N-[5-(4-nitrophenyl)-4-[5-[(3,4,5,6-tetrahydro-2H-azepin-7-yl)amino]pent yl]-2-thiazolyl]-, monohydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

O-methylcaprolactim (2525-16-8) → 2-Acetylamino-4-<5-(azepin-2-ylideneaminopentyl)>-5-(4-nitrophenyl)-1,3-thiazole hydrobromide (143602-38-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 31 percent / acetonitrile / 2 h / Heating

2: 48 percent / 0.42 h / Heating

In acetonitrile;

DOI:10.1055/s-1992-26197

Reference yield:

S-(4-nitrobenzyl)isothiourea hydrobromide (64039-36-7) → 2-Acetylamino-4-<5-(azepin-2-ylideneaminopentyl)>-5-(4-nitrophenyl)-1,3-thiazole hydrobromide (143602-38-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 31 percent / acetonitrile / 2 h / Heating

2: 48 percent / 0.42 h / Heating

In acetonitrile;

DOI:10.1055/s-1992-26197

upstream raw materials:

O-methylcaprolactim

S-(4-nitrobenzyl)isothiourea hydrobromide

Refernces