Phosphine oxide, butyldiphenyl-

Base Information

• Chemical Name: Phosphine oxide, butyldiphenyl-
• CAS No.: 4233-13-0
• Molecular Formula: C16H19OP
• Molecular Weight: 258.3
• DSSTox Substance ID: DTXSID80195140
• Nikkaji Number: J1.148.729G
• Wikidata: Q83068013
• Mol file: 4233-13-0.mol

Synonyms:Butyldiphenylphosphine oxide;Phosphine oxide, butyldiphenyl-;BRN 0913931;4233-13-0;(diphenylphosphoryl)butan;Butyl(diphenyl)phosphine oxide;SCHEMBL780075;Butyl(diphenyl)phosphine oxide #;DTXSID80195140;AKOS024322896;LS-105985

Chemical Property of Phosphine oxide, butyldiphenyl-

Chemical Property:

• Vapor Pressure: 6.76E-05mmHg at 25°C
• Boiling Point: 354.6°Cat760mmHg
• Flash Point: 168.3°C
• Density: 1.06g/cm³
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 5
• Exact Mass: 258.117352223
• Heavy Atom Count: 18
• Complexity: 253

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCP(=O)(C1=CC=CC=C1)C2=CC=CC=C2

Technology Process of Phosphine oxide, butyldiphenyl-

There total 51 articles about Phosphine oxide, butyldiphenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

n-butyl(triphenyl)phosphonium bromide (1779-51-7) → butyldiphenylphosphine oxide (4233-13-0)

Guidance literature:

With air; potassium tert-butylate; In acetonitrile; for 2h;

DOI:10.1139/V08-056

Reference yield: 97.0%

1-bromo-butane (109-65-9) + Diphenylphosphine oxide (4559-70-0) → butyldiphenylphosphine oxide (4233-13-0)

Guidance literature:

With potassium hydroxide; tetra-(n-butyl)ammonium iodide; In benzene; at 80 ℃; for 2h;

DOI:10.1055/s-1986-31510

Reference yield: 97.0%

n-butyllithium (109-72-8,29786-93-4) + Triphenylphosphine oxide (791-28-6) → butyldiphenylphosphine oxide (4233-13-0)

Guidance literature:

In tetrahydrofuran; hexane; cyclohexane; at -78 - 20 ℃; for 24h; Inert atmosphere; Schlenk technique;

DOI:10.1016/j.tet.2015.12.043

upstream raw materials:

diphenyl-phosphinic acid

n-butyl-diphenylphosphane

n-butyl(triphenyl)phosphonium bromide

n-Butyl chloride

Downstream raw materials:

2-(Diphenyl-phosphinoyl)-1-(4-methoxy-phenyl)-pentan-1-ol

(diphenylphosphinobutyl)diphenylphosphine oxide

n-butyldicyclohexylphosphine oxide

n-butyl-diphenylphosphane

Refernces

• 1、 Zhang, Jian-Qiu,Han, Li-Biao. "Reductive conversion of phosphoryl P(O) compounds to trivalent organophosphines R3P". . . Retrieved 2021/02/20.
• 2、 Zhang, Jian-Qiu,Ikawa, Eiichi,Fujino, Hiroyoshi,Naganawa, Yuki,Nakajima, Yumiko,Han, Li-Biao. "Selective C-P(O) Bond Cleavage of Organophosphine Oxides by Sodium". supporting information. p. 14166 - 14173. Retrieved 2020/11/13.