Methylmethionine iodide

Base Information

• Chemical Name: Methylmethionine iodide
• CAS No.: 3493-11-6
• Molecular Formula: C6H14 N O2 S . I
• Molecular Weight: 291.153
• Hs Code.: 2930909090
• European Community (EC) Number: 251-893-0
• UNII: 7O2D9U053L
• Wikidata: Q27268629
• Metabolomics Workbench ID: 166264
• ChEMBL ID: CHEMBL540394
• Mol file: 3493-11-6.mol

Synonyms:METHYLMETHIONINE IODIDE;L-METHIONINE METHYLSULFONIUM IODIDE;3493-11-6;7O2D9U053L;[(3S)-3-amino-3-carboxypropyl]-dimethylsulfanium;iodide;(S)-(3-Amino-3-carboxypropyl)dimethylsulfonium iodide;CHEMBL540394;[(3S)-3-Amino-3-carboxypropyl](dimethyl)-sulfonium iodide;LOBARTHROSE;METHIONINE-S-METHYLSULFONIUM IODIDE CRYSTALLINE;VITAMIN U IODIDE;34236-06-1;METHIONINE METHIODIDE;MLS006012027;UNII-7O2D9U053L;CHEBI:195174;L-methionine-methylsulfonium-iodide;AKOS015907820;SMR004703560;METHYLMETHIONINE SULFONIUM IODIDE, L-;Q27268629;[(3S)-3-amino-3-carboxypropyl]-dimethylsulanium;[(3S)-3-amino-3-carboxypropyl]dimethylsulfanium iodide;Sulfonium, (3-amino-3-carboxypropyl)dimethyl-, iodide, (S)-;SULFONIUM, ((3S)-3-AMINO-3-CARBOXYPROPYL)DIMETHYL-, IODIDE (1:1)

Chemical Property of Methylmethionine iodide

Chemical Property:

• Melting Point: 150 °C (decomp)
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 88.62000
• Density: g/cm³
• LogP: -2.62940
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 290.97900
• Heavy Atom Count: 11
• Complexity: 116

Purity/Quality:

99% ^*data from raw suppliers

[(3S)-3-Amino-3-carboxypropyl](dimethyl)-sulfonium iodide ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[S+](C)CCC(C(=O)O)N.[I-]
• Isomeric SMILES: C[S+](C)CC[C@@H](C(=O)O)N.[I-]

Technology Process of Methylmethionine iodide

There total 3 articles about Methylmethionine iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

L-methionine (63-68-3,26062-47-5,58576-49-1) + methyl iodide (74-88-4) → (3S)-(3-amino-3-carboxypropyl)dimethylsulfonium iodide (3493-11-6)

Guidance literature:

In water; at 40 ℃; for 4h;

Reference yield: 78.0%

(+)-methionine (59-51-8,63-68-3,348-67-4,7005-18-7,37654-22-1,98758-24-8,26062-47-5,58576-49-1) + methyl iodide (74-88-4) → (3S)-(3-amino-3-carboxypropyl)dimethylsulfonium iodide (3493-11-6)

Guidance literature:

With formic acid; acetic acid; at 20 ℃; for 72h;

Reference yield:

(S-tert-butyl)-homocysteine (62965-24-6) + methyl iodide (74-88-4) → (3S)-(3-amino-3-carboxypropyl)dimethylsulfonium iodide (3493-11-6)

Guidance literature:

In water; for 2h; Ambient temperature;

DOI:10.1016/S0040-4039(00)89163-7

upstream raw materials:

L-methionine

methyl iodide

(+)-methionine

(S-tert-butyl)-homocysteine

Downstream raw materials:

DL-Homoserine

Seleno-L-methionine

L-homoserine

(l)α-amino-γ-butyrolactone hydroiodide

Refernces

• 1、 -. "Method for preparing L-selenomethionine". Paragraph 0011; 0016. . Retrieved 2020/02/17.
• 2、 Hossain, Mohammad Anwar,Sattenapally, Narsimha,Parikh, Hardik I.,Li, Wei,Rumbaugh, Kendra P.,German, Nadezhda A.. "Design, synthesis, and evaluation of compounds capable of reducing Pseudomonas aeruginosa virulence". supporting information. . Retrieved 2019/11/26.