Technology Process of Benzene, 1-ethynyl-3-(phenylethynyl)-
There total 6 articles about Benzene, 1-ethynyl-3-(phenylethynyl)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
phenylethynyl diphenylphosphine oxide;
With
potassium tert-butylate; tributyltin methoxide;
In
tetrahydrofuran;
for 4.5h;
Inert atmosphere;
Reflux;
3-iodo phenylacetylene;
With
tris-(dibenzylideneacetone)dipalladium(0); tri-tert-butyl phosphine;
In
tetrahydrofuran;
at 20 ℃;
for 8h;
Inert atmosphere;
DOI:10.3184/174751918X15258743466204
- Guidance literature:
-
With
methanol; tetra(n-butyl)ammonium hydroxide;
In
toluene;
at 75 ℃;
for 0.0833333h;
Inert atmosphere;
DOI:10.3762/bjoc.7.55
- Guidance literature:
-
phenylethynyl diphenylphosphine oxide;
With
potassium tert-butylate; tributyltin methoxide;
In
tetrahydrofuran;
for 4.5h;
Inert atmosphere;
Reflux;
3-bromophenylacetylene;
With
tris-(dibenzylideneacetone)dipalladium(0); tri-tert-butyl phosphine;
In
tetrahydrofuran;
at 20 ℃;
for 8h;
Reagent/catalyst;
Solvent;
Temperature;
Time;
Inert atmosphere;
DOI:10.3184/174751918X15258743466204