Bis(2-methylphenoxy)(oxo)phosphanium

Base Information

• Chemical Name: Bis(2-methylphenoxy)(oxo)phosphanium
• CAS No.: 15516-38-8
• Molecular Formula: C14H15O3P
• Molecular Weight: 262.245
• DSSTox Substance ID: DTXSID50442517
• Wikidata: Q82259826
• Mol file: 15516-38-8.mol

Synonyms:SCHEMBL3281430;DTXSID50442517;Bis(2-methylphenoxy)(oxo)phosphanium;15516-38-8

Chemical Property of Bis(2-methylphenoxy)(oxo)phosphanium

Chemical Property:

• XLogP3: 3.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 261.06805630
• Heavy Atom Count: 18
• Complexity: 256

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=CC=C1O[P+](=O)OC2=CC=CC=C2C

Technology Process of Bis(2-methylphenoxy)(oxo)phosphanium

There total 5 articles about Bis(2-methylphenoxy)(oxo)phosphanium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ortho-cresol (95-48-7,77504-84-8) → di-o-methylphenyl phosphonate (15516-38-8)

Guidance literature:

ortho-cresol; With 1H-imidazole; phosphorus trichloride; In dichloromethane; at 0 ℃; for 0.5h;

With water; Further stages.;

DOI:10.1021/jo000068x

Reference yield:

tri(O-methylphenyl)phosphite (2622-08-4) → di-o-methylphenyl phosphonate (15516-38-8)

Guidance literature:

With phosphonic Acid;

DOI:10.1021/ja01521a028

Reference yield:

bis(o-tolyl) chlorophosphite (22277-50-5) → di-o-methylphenyl phosphonate (15516-38-8)

Guidance literature:

With water; In dichloromethane;

DOI:10.1021/jo050352u

upstream raw materials:

tri(O-methylphenyl)phosphite

ortho-cresol

bis(o-tolyl) chlorophosphite

Downstream raw materials:

[(Hydroxy-o-tolyloxy-phosphorylmethyl)-amino]-acetic acid ethyl ester

[(Bis-o-tolyloxy-phosphorylmethyl)-amino]-acetic acid ethyl ester

ethyl di-O-tolylphosphonoacetate

C₁₆H₁₇O₅P

Refernces

• 1、 Dias, Luiz C.,Meira, Paulo R. R.. "Total synthesis of the potent antitumor polyketide (-)-callystatin A". . p. 4762 - 4773. Retrieved 2007/10/03.