Technology Process of 4'-n-Hexyloxybiphenyl-4-boronic acid, 97%
There total 8 articles about 4'-n-Hexyloxybiphenyl-4-boronic acid, 97% which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
4-bromo-4'-(n-hexyl-1-oxy)-1,1'-biphenyl;
With
n-butyllithium;
In
tert-butyl methyl ether;
at -20 ℃;
for 2h;
Inert atmosphere;
With
Triisopropyl borate;
In
tetrahydrofuran; tert-butyl methyl ether;
at -60 - 20 ℃;
Inert atmosphere;
With
hydrogenchloride;
In
tetrahydrofuran; tert-butyl methyl ether; water;
at 20 ℃;
for 0.166667h;
DOI:10.1016/j.tet.2012.02.015
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 86.3 percent / sodium hydroxide / ethanol; H2O / 1 h / Heating
2.1: n-BuLi / tetrahydrofuran; hexane / -78 - -65 °C
2.2: B(OCH3)3 / tetrahydrofuran; hexane / -65 - 20 °C
2.3: aq. HCl / tetrahydrofuran; hexane / 1 h / 20 °C
With
sodium hydroxide; n-butyllithium;
In
tetrahydrofuran; ethanol; hexane; water;
DOI:10.1080/10587250008031039
