2-prop-2-enoxybenzamide

Base Information

• Chemical Name: 2-prop-2-enoxybenzamide
• CAS No.: 14520-53-7
• Molecular Formula: C10H11 N O2
• Molecular Weight: 177.203
• Hs Code.: 2924299090
• Mol file: 14520-53-7.mol

Synonyms:Benzamide,2-(2-propenyloxy)- (9CI); Benzamide, 2-(allyloxy)- (8CI); Benzamide,o-(allyloxy)- (6CI,7CI); 2-Allyloxybenzamide; o-(Allyloxy)benzamide

Chemical Property of 2-prop-2-enoxybenzamide

Chemical Property:

• Vapor Pressure: 0.000225mmHg at 25°C
• Refractive Index: 1.5168 (estimate)
• Boiling Point: 325.8°C at 760 mmHg
• Flash Point: 166°C
• PSA: 53.31000
• Density: 1.105g/cm³
• LogP: 2.23450

Purity/Quality:

99% ^*data from raw suppliers

2-ALLYLOXYBENZAMIDE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-prop-2-enoxybenzamide

There total 5 articles about 2-prop-2-enoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

2-(prop-2'-enyloxy)benzonitrile (97960-34-4) → 2-(prop-2'-enyloxy)benzamide (14520-53-7)

Guidance literature:

With dihydrogen peroxide; potassium carbonate; exothermic reaction;

DOI:10.1071/CH9960219

Reference yield: 67.0%

2-Bromobenzamide (4001-73-4) + allyl alcohol (107-18-6) → 2-(prop-2'-enyloxy)benzamide (14520-53-7) + 2-[2-(allyloxy)phenyl]quinazolin-4(3H)-one

Guidance literature:

With copper(l) iodide; caesium carbonate; at 120 ℃; for 0.166667h; under 9308.91 Torr; Microwave irradiation;

DOI:10.1002/ejoc.201800660

Reference yield:

2-fluorobenzamide (445-28-3) + allyl alcohol (107-18-6) → 2-(prop-2'-enyloxy)benzamide (14520-53-7)

Guidance literature:

With copper diacetate; caesium carbonate; at 120 ℃; for 0.166667h; under 9308.91 Torr; Microwave irradiation;

DOI:10.1002/ejoc.201800660

upstream raw materials:

allyl bromide

salicylamide

2-(prop-2'-enyloxy)benzonitrile

2-Bromobenzamide

Downstream raw materials:

2-Phenyl-1,2,4,10-tetrahydro-9-oxa-4-aza-phenanthren-3-one

2-(prop-2'-enyloxy)benzonitrile

2,2-Bis(trifluormethyl)-2,3,3a,4-tetrahydrobenzpyranopyrrol

salicylamide

Refernces

• 1、 Campi, Eva M.,Jackson, W. Roy,McCubbin, Quentin J.,Trnacek, Andrew E.. "The stereochemistry of organometallic compounds. XLIII* rhodium-catalysed reactions of 2-(alkenyloxy)benzylamines and 2-(N-allyl-N-benzylamino)benzylamine". . p. 219 - 230. Retrieved 2007/10/03.