Hexanoic acid, 6-isothiocyanato-

Base Information

• Chemical Name: Hexanoic acid, 6-isothiocyanato-
• CAS No.: 16424-04-7
• Molecular Formula: C7H11NO2S
• Mol file: 16424-04-7.mol

Synonyms:

Chemical Property of Hexanoic acid, 6-isothiocyanato-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Hexanoic acid, 6-isothiocyanato-

There total 1 articles about Hexanoic acid, 6-isothiocyanato- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-aminohexanoic acid (60-32-2,93208-38-9) → 6,6'-thioureylene-di-hexanoic acid (6630-05-3) + 6-isothiocyanato-hexanoic acid (16424-04-7)

Guidance literature:

With sodium hydroxide; beim Behandeln des Reaktionsprodukts mit PbO, Blei(II)-acetat und H₂O;

DOI:10.1021/ja01546a035

Reference yield:

6-isothiocyanato-hexanoic acid (16424-04-7) + benzoic acid hydrazide (613-94-5) → C14H19N3O3S

Guidance literature:

In N,N-dimethyl-formamide; at 55 ℃; Sealed tube;

DOI:10.1016/j.bioorg.2021.105024

Reference yield:

6-isothiocyanato-hexanoic acid (16424-04-7) → 6-Isothiocyanatohexansaeurechlorid (39243-52-2)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / ethyl acetate

2: SOCl₂ / CHCl₃ / Heating

With thionyl chloride; triethylamine; In chloroform; ethyl acetate;

upstream raw materials:

6-aminohexanoic acid

Downstream raw materials:

C₁₇H₂₄N₄O₄S

6-Isothiocyanatohexansaeurechlorid