5-(1-Ethoxyethyl)-5-ethylbarbituric acid

Base Information

• Chemical Name: 5-(1-Ethoxyethyl)-5-ethylbarbituric acid
• CAS No.: 66941-21-7
• Molecular Formula: C10H16N2O4
• Molecular Weight: 228.245
• Mol file: 66941-21-7.mol

Synonyms:5-(1-Aethoxy-aethyl)-5-aethyl-barbitursaeure;5-(1-Ethoxyethyl)-5-ethylbarbituric acid;BARBITURIC ACID,5-(1-ETHOXYETHYL)-5-ETHYL;

Chemical Property of 5-(1-Ethoxyethyl)-5-ethylbarbituric acid

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 91.48000
• Density: 1.147g/cm³
• LogP: 0.72560

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-(1-Ethoxyethyl)-5-ethylbarbituric acid

There total 5 articles about 5-(1-Ethoxyethyl)-5-ethylbarbituric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(1-ethoxy-ethyl)-ethyl-malonic acid diethyl ester (854833-89-9) + urea (57-13-6) → 5-(1-ethoxy-ethyl)-5-ethyl-barbituric acid (66941-21-7)

Guidance literature:

With sodium ethanolate;

Reference yield:

(1-ethoxy-vinyl)-malonic acid diethyl ester (854838-42-9) → 5-(1-ethoxy-ethyl)-5-ethyl-barbituric acid (66941-21-7)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium tert-butylate

2: Raney nickel; ethanol / 120 °C / 95616 Torr / Hydrogenation

3: sodium ethylate

With ethanol; sodium ethanolate; nickel; sodium t-butanolate;

Reference yield:

diethyl 2-(1-ethoxyethylidene)malonate (3044-06-2) → 5-(1-ethoxy-ethyl)-5-ethyl-barbituric acid (66941-21-7)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium tert-butylate

2: Raney nickel; ethanol / 120 °C / 95616 Torr / Hydrogenation

3: sodium ethylate

With ethanol; sodium ethanolate; nickel; sodium t-butanolate;

upstream raw materials:

(1-ethoxy-ethyl)-ethyl-malonic acid diethyl ester

urea

(1-ethoxy-vinyl)-malonic acid diethyl ester

(1-ethoxy-vinyl)-ethyl-malonic acid diethyl ester