Benzenamine, 4-fluoro-N,N-dimethyl-3-nitro-

Base Information

• Chemical Name: Benzenamine, 4-fluoro-N,N-dimethyl-3-nitro-
• CAS No.: 18542-98-8
• Molecular Formula: C8H9FN2O2
• Molecular Weight: 184.17
• Mol file: 18542-98-8.mol

Synonyms:(4-Fluoro-3-nitro-phenyl)-dimethyl-amine;(4-fluoro-3-nitrophenyl)-dimethyl-amine;4-Fluor-3-nitro-N.N-dimethyl-anilin;N,N-dimethyl-3-nitro-4-fluoroaniline;N,N-Dimethyl-4-fluor-3-nitroanilin;(4-fluoro-3-nitrophenyl)-dimethylamine;

Chemical Property of Benzenamine, 4-fluoro-N,N-dimethyl-3-nitro-

Chemical Property:

• PSA: 49.06000
• LogP: 2.32310

Purity/Quality:

99% ^*data from raw suppliers

4-Fluoro-N,N-dimethyl-3-nitroaniline 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenamine, 4-fluoro-N,N-dimethyl-3-nitro-

There total 2 articles about Benzenamine, 4-fluoro-N,N-dimethyl-3-nitro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-Fluoro-3-nitroaniline (364-76-1) + methyl iodide (74-88-4) → 4-fluoro-N,N-dimethyl-3-nitroaniline (18542-98-8)

Guidance literature:

4-Fluoro-3-nitroaniline; With sodium hydride; In N,N-dimethyl-formamide; paraffin oil; at 0 - 20 ℃; for 0.5h;

methyl iodide; In N,N-dimethyl-formamide; paraffin oil; at 0 ℃; for 4h;

DOI:10.1002/anie.201907837

Reference yield:

→ 4-fluoro-N,N-dimethyl-3-nitroaniline (18542-98-8)

Guidance literature:

p-Fluor-N.N-dimethyl-anilin, HNO3-H2SO4;

DOI:10.1021/jo01256a004

Reference yield: 100.0%

4-fluoro-N,N-dimethyl-3-nitroaniline (18542-98-8) → 4-fluoro-N1,N1-dimethylbenzene-1,3-diamine (192819-46-8)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 12h; under 760.051 Torr;

DOI:10.1002/anie.201907837

upstream raw materials:

4-Fluoro-3-nitroaniline

methyl iodide

Downstream raw materials:

C₈H₉FN₂O₃

4-fluoro-N₁,N₁-dimethylbenzene-1,3-diamine

1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]urea

Refernces

• 1、 -. "MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO". Page/Page column 74; 241. . Retrieved 2021/02/12.
• 2、 -. "NOVEL SULFONAMIDE COMPOUNDS". Page/Page column 9. . Retrieved 2009/12/02.