N-Carbobenzoxy-L-glutamic acid

Base Information Edit

Chemical Name:N-Carbobenzoxy-L-glutamic acid
CAS No.:1155-62-0
Deprecated CAS:22259-07-0
Molecular Formula:C13H15NO6
Molecular Weight:281.265
Hs Code.:29242990
European Community (EC) Number:214-584-1,829-666-8
DSSTox Substance ID:DTXSID70883660
Nikkaji Number:J80.207G
Wikidata:Q72441968
ChEMBL ID:CHEMBL355760
Mol file:1155-62-0.mol

Synonyms:1155-62-0;N-Cbz-L-glutamic acid;N-Carbobenzoxy-L-glutamic acid;Z-Glu-OH;N-Benzyloxycarbonyl-L-glutamic acid;Carbobenzoxy-L-glutamic acid;N-Carbobenzyloxy-l-glutamic acid;L-Glutamic acid, N-[(phenylmethoxy)carbonyl]-;BENZYLOXYCARBONYL-L-GLUTAMIC ACID;N-Benzyloxycarbonylglutamic acid;(2S)-2-(phenylmethoxycarbonylamino)pentanedioic acid;NSC 555;NSC 88494;N-(Benzyloxycarbonyl)-L-glutamic acid;Glutamic acid, N-[(phenylmethoxy)carbonyl]-;Glutamic acid, N-carboxy-, N-benzyl ester, L-;Cbz-Glu-OH;EINECS 214-584-1;(S)-2-(((BENZYLOXY)CARBONYL)AMINO)PENTANEDIOIC ACID;(2S)-2-{[(benzyloxy)carbonyl]amino}pentanedioic acid;N-((Phenylmethoxycarbonyl)-L-glutamic acid;N-((Phenylmethoxy)carbonyl)-L-glutamic acid;L-Glutamic acid, N-((phenylmethoxy)carbonyl)-;MFCD00002801;Z-L-Glutamic acid;63648-73-7;N-(Carbobenzyloxy)-L-glutamic acid;N-[(PHENYLMETHOXY)CARBONYL]-L-GLUTAMIC ACID;Cbz-L-Glu;n-cbz-glutamic acid;Z-Glu;Z-L-Glu;N-carbobenzoxy glutamic acid;Z-Glu-OH, 99%;SCHEMBL910233;UPCMLD00WCRH4-129;CHEMBL355760;BDBM36120;PVFCXMDXBIEMQG-JTQLQIEISA-;DTXSID70883660;((Benzyloxy)carbonyl)-L-glutamic acid;AKOS010397338;AKOS015836890;N-benzyloxycarbonyl-(L)-glutamic acid;CS-W020668;FD21351;N-Benzyloxycarbonylglutamic acid, (L)-;2-Benzyloxycarbonylamino-pentanedioic acid;AC-26243;CS-17392;HY-20165;N-[Phenylmethoxycarbonyl]-L-glutamic acid;(s)-2-(benzyloxycarbonylamino)pentanedioic acid;EN300-149212;M03047;J-300102;Z756446340;N-alpha-BenZyloxycarbonyl-L-glutamic-acid (CbZ-L-Glu-OH)

Suppliers and Price of N-Carbobenzoxy-L-glutamic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Z-Glu
5g
$ 362.00

TRC
N-Carbobenzyloxy-L-glutamicAcid
5g
$ 50.00

TRC
N-Carbobenzyloxy-L-glutamicAcid
250g
$ 545.00

TCI Chemical
N-Carbobenzoxy-L-glutamic Acid >98.0%(T)
100g
$ 253.00

TCI Chemical
N-Carbobenzoxy-L-glutamic Acid >98.0%(T)
25g
$ 64.00

Sigma-Aldrich
Z-Glu-OH 99%
25g
$ 63.00

Matrix Scientific
N-[(Benzyloxy)carbonyl]glutamic acid
500mg
$ 158.00

Iris Biotech GmbH
Z-L-Glu-OH
25 g
$ 67.50

Frontier Specialty Chemicals
N-Cbz-L-glutamicacid 99%
25g
$ 95.00

Frontier Specialty Chemicals
N-Cbz-L-glutamicacid 99%
100g
$ 245.00

Total 123 raw suppliers

Chemical Property of N-Carbobenzoxy-L-glutamic acid Edit

Chemical Property:

Appearance/Colour:off-white solid
Vapor Pressure:5.03E-12mmHg at 25°C
Melting Point:115-117 °C(lit.)
Refractive Index:-7.5 ° (C=8, AcOH)
Boiling Point:529.1 °C at 760 mmHg
PKA:3.81±0.10(Predicted)
Flash Point:273.8 °C
PSA：112.93000
Density:1.36 g/cm³
LogP:1.62170
Storage Temp.:−20°C
Solubility.:DMF, Methanol
XLogP3:0.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:8
Exact Mass:281.08993720
Heavy Atom Count:20
Complexity:351

Purity/Quality:

99% ^*data from raw suppliers

Z-Glu ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 20/21/22-36/37/38
Safety Statements: 22-24/25-36-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC(=O)NC(CCC(=O)O)C(=O)O
Isomeric SMILES:C1=CC=C(C=C1)COC(=O)N[C@@H](CCC(=O)O)C(=O)O
Uses N-Cbz-L-glutamic acid is used for the synthesis. Used for the synthesis of carboxyalkyl peptides as inhibitors of angiotensin-converting enzyme of human blood serum.

Technology Process of N-Carbobenzoxy-L-glutamic acid

There total 67 articles about N-Carbobenzoxy-L-glutamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 15231-21-7
(S)-2-((phenylmethoxycarbonyl)amino)-4-cyanobutanoic acid

: 1155-62-0
N-benzyloxycarbonyl-L-glutamic acid

Guidance literature:: (S)-2-((phenylmethoxycarbonyl)amino)-4-cyanobutanoic acid; With dihydrogen peroxide; sodium hydroxide; In water; at 20 ℃; for 0.5h;

With hydrogenchloride; In water; at 0 ℃; pH=2;
DOI:10.1016/j.tetlet.2011.08.017