3-Methoxy-1,2-benzisothiazole 1,1-dioxide

Base Information

• Chemical Name: 3-Methoxy-1,2-benzisothiazole 1,1-dioxide
• CAS No.: 18712-14-6
• Molecular Formula: C8H7NO3S
• Molecular Weight: 197.214
• Hs Code.: 2934991000
• Mol file: 18712-14-6.mol

Synonyms:Saccharin O-methyl ether;3-Methoxy-benzisothiazol-S-dioxid;1,2-Benzisothiazole,3-methoxy-,1,1-dioxide;

Chemical Property of 3-Methoxy-1,2-benzisothiazole 1,1-dioxide

Chemical Property:

• Melting Point: 182 °C
• Boiling Point: 349.8±25.0 °C(Predicted)
• PKA: -5.10±0.20(Predicted)
• PSA: 64.11000
• Density: 1.46±0.1 g/cm3(Predicted)
• LogP: 1.29830
• Storage Temp.: 2-8°C
• Solubility.: DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

98%min ^*data from raw suppliers

3-Methoxy-1,2-benzothiazole1,1-dioxide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Methoxy-1,2-benzisothiazole 1,1-dioxide

There total 6 articles about 3-Methoxy-1,2-benzisothiazole 1,1-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

methanol (67-56-1) + 3-chloro-1,2-benzisothiazole 1,1-dioxide (567-19-1) → 3-(methoxy)-1,2-benzisothiazole 1,1-dioxide (18712-14-6)

Guidance literature:

at 20 ℃;

DOI:10.1016/j.molstruc.2007.06.004

Reference yield:

Metsulfuron-methyl (74223-64-6) → benzoic acid methyl ester (93-58-3,5705-52-2,80226-58-0) + methyl 2-(aminosulfonyl)benzoate (57683-71-3) + 2-(methoxycarbonyl)benzenesulfonyl isocyanate (74222-95-0) + 4-methoxy-6-methyl-1,3,5-triazin-2-amine (1668-54-8) + 2-Isocyanato-4-methoxy-6-methyl-[1,3,5]triazine + 3-(methoxy)-1,2-benzisothiazole 1,1-dioxide (18712-14-6)

Guidance literature:

at 800 ℃; for 0.00138889h; Product distribution; study of the pyrolysis of various sulfonylureas; other sulfonylureas and their products;

DOI:10.1002/jms.1190300216

Reference yield:

methyl iodide (74-88-4) → 3-(methoxy)-1,2-benzisothiazole 1,1-dioxide (18712-14-6)

Guidance literature:

With diethyl ether; at 100 ℃; im Rohr;

upstream raw materials:

methanol

Metsulfuron-methyl

diazomethane

saccharin

Downstream raw materials:

N-methylsaccharin

Refernces

• 1、 Galletti,Dinelli,Chiavari. "Collection of ion-trap mass spectre of sulfonylurea pyrolysis products". . p. 333 - 338. Retrieved 2007/10/02.