2-Ethyl-5-methylfuran

Base Information

• Chemical Name: 2-Ethyl-5-methylfuran
• CAS No.: 1703-52-2
• Molecular Formula: C7H10O
• Molecular Weight: 110.156
• Hs Code.: 2932190090
• European Community (EC) Number: 216-937-5
• UNII: PG4BLD3EJI
• DSSTox Substance ID: DTXSID80168839
• Nikkaji Number: J45.571G
• Wikidata: Q27160507
• Metabolomics Workbench ID: 44016
• Mol file: 1703-52-2.mol

Synonyms:2-Ethyl-5-methylfuran;1703-52-2;Furan, 2-ethyl-5-methyl-;2-Methyl-5-ethylfuran;2-Ethyl-5-methyl-furan;PG4BLD3EJI;EINECS 216-937-5;UNII-PG4BLD3EJI;2-ethyl-5-methyl furan;furan, 2-methyl, 5-ethyl;SCHEMBL144611;5-METHYL-2-ETHYLFURAN;CHEBI:88617;DTXSID80168839;AKOS006228280;SB61677;AS-57447;CS-0333891;Q27160507

Chemical Property of 2-Ethyl-5-methylfuran

Chemical Property:

• Vapor Pressure: 19.3mmHg at 25°C
• Refractive Index: n20/D 1.447(lit.)
• Boiling Point: 119.1 °C at 760 mmHg
• Flash Point: 15.1 °C
• PSA: 13.14000
• Density: 0.907 g/cm³
• LogP: 2.15040
• Storage Temp.: 2-8°C
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 110.073164938
• Heavy Atom Count: 8
• Complexity: 70.8

Purity/Quality:

98% ^*data from raw suppliers

2-Ethyl-5-methylfuran 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F, Xn
• Hazard Codes: F,Xn
• Statements: 11-20/21/22
• Safety Statements: 16-36

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Other Classes -> Ethers, Other
• Canonical SMILES: CCC1=CC=C(O1)C

Technology Process of 2-Ethyl-5-methylfuran

There total 15 articles about 2-Ethyl-5-methylfuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

2-acetyl-5-methylfuran (1193-79-9) → 2-ethyl-5-methylfuran (1703-52-2)

Guidance literature:

With hydrogen; In tetrahydrofuran; at 260 ℃; for 4h; Temperature; Solvent;

Reference yield: 69.0%

methyl 2-(1-(5-methylfuran-2-yl)ethylidene)hydrazine-1-carboxylate → 2-ethyl-5-methylfuran (1703-52-2)

Guidance literature:

With potassium hydroxide; In 2,2'-[1,2-ethanediylbis(oxy)]bisethanol; at 140 ℃; for 4h;

DOI:10.1055/s-0035-1560805

Reference yield: 61.0%

2-methylfuran (534-22-5) + ethyl iodide (75-03-6) → 2-ethyl-5-methylfuran (1703-52-2)

Guidance literature:

2-methylfuran; With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 20 ℃; Inert atmosphere;

ethyl iodide; In tetrahydrofuran; hexane; for 24h; Inert atmosphere;

DOI:10.1039/c1gc15810d

upstream raw materials:

2-acetyl-5-methylfuran

5-ethyl-2-methyl-furan-3-carboxylic acid

propionaldehyde

1-lithio-3-methoxy-1,2-butadiene

Downstream raw materials:

2,3-dimethylcyclopent-2-enone

furan-2,5-dicarboxylic acid

4-methylethylbenzene

(3aα,4β,7β,7aα)-4-Ethylhexahydro-7-methyl-4,7-epoxyisobenzofuran-1,3-dione

Refernces

• 1、 -. "METAL CATALYST AND HYDROGEN GAS FREE APPROACHES FOR SELECTIVE REDUCTION OF ALDEHYDE TO METHYL GROUP OF DIFFERENT SUBSTITUTED FURANS". Page/Page column 18-19. . Retrieved 2021/08/27.
• 2、 Koehle, Maura,Sara?i, Erisa,Dauenhauer, Paul,Lobo, Raul F.. "Production of p-Methylstyrene and p-Divinylbenzene from Furanic Compounds". . p. 91 - 98. Retrieved 2017/01/17.