Technology Process of 2-Benzofurancarboxylic acid,
5-[2-[1-(triphenylmethyl)-1H-tetrazol-5-yl]phenyl]-, ethyl ester
There total 4 articles about 2-Benzofurancarboxylic acid,
5-[2-[1-(triphenylmethyl)-1H-tetrazol-5-yl]phenyl]-, ethyl ester which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
palladium diacetate; potassium carbonate; triphenylphosphine;
In
tetrahydrofuran; 1,2-dimethoxyethane;
for 5h;
Heating;
DOI:10.1016/S0968-0896(96)00244-1
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 79.3 percent / Br2 / CS2 / 50 °C
2: 1.) NaH / 1.) DMF, 30 min, 2.) DMF, 2 h
3: 1.) NaOEt, 2.) H2SO4 / 1.) EtOH, reflux, 3 h, 2.) EtOH, reflux, 1 h
4: 93 percent / Pd(OAc)2, PPh3, aq. K2CO3 / tetrahydrofuran; 1,2-dimethoxy-ethane / 5 h / Heating
With
palladium diacetate; sulfuric acid; bromine; sodium ethanolate; sodium hydride; potassium carbonate; triphenylphosphine;
In
tetrahydrofuran; carbon disulfide; 1,2-dimethoxyethane;
DOI:10.1016/S0968-0896(96)00244-1
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.) NaOEt, 2.) H2SO4 / 1.) EtOH, reflux, 3 h, 2.) EtOH, reflux, 1 h
2: 93 percent / Pd(OAc)2, PPh3, aq. K2CO3 / tetrahydrofuran; 1,2-dimethoxy-ethane / 5 h / Heating
With
palladium diacetate; sulfuric acid; sodium ethanolate; potassium carbonate; triphenylphosphine;
In
tetrahydrofuran; 1,2-dimethoxyethane;
DOI:10.1016/S0968-0896(96)00244-1