ALPHA-D-GALACTOSE-1-PHOSPHATE DIPOTASSIUM SALT DIHYDRATE

Base Information

• Chemical Name: ALPHA-D-GALACTOSE-1-PHOSPHATE DIPOTASSIUM SALT DIHYDRATE
• CAS No.: 19046-60-7
• Molecular Formula: C6H13 O9 P . 2 K
• Molecular Weight: 336.318
• Hs Code.: 29400090
• European Community (EC) Number: 242-783-3
• DSSTox Substance ID: DTXSID80940612
• Nikkaji Number: J224.846H
• Mol file: 19046-60-7.mol

Synonyms:Galactopyranose,1-(dihydrogen phosphate), dipotassium salt, a-D- (8CI); Galactopyranose, 1-phosphate, dipotassiumsalt (7CI); Galactose 1-phosphate dipotassium salt

Chemical Property of ALPHA-D-GALACTOSE-1-PHOSPHATE DIPOTASSIUM SALT DIHYDRATE

Chemical Property:

• Boiling Point: 603°Cat760mmHg
• Flash Point: 318.5°C
• PSA: 172.38000
• Density: g/cm³
• LogP: -2.22800
• Storage Temp.: −20°C
• Solubility.: H2O: 50 mg/mL, clear, colorless
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 2
• Exact Mass: 335.9414819
• Heavy Atom Count: 18
• Complexity: 266

Purity/Quality:

99%, ^*data from raw suppliers

a-D-Galactose-1-phosphate dipotassium salt hydrate ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(C1C(C(C(C(O1)OP(=O)([O-])[O-])O)O)O)O.[K+].[K+]
• Isomeric SMILES: C([C@@H]1[C@@H]([C@@H]([C@H]([C@H](O1)OP(=O)([O-])[O-])O)O)O)O.[K+].[K+]
• Description: α-D-Galactose-1-phosphate is an intermediate in the interconversion of glucose and galactose. It is produced from galactose by galactokinase. Galactose-1-phosphate uridyl transferase reversibly catalyzes the conversion of UDP-glucose ( and galactose-1-phosphate to glucose-1-phosphate and UDP-galactose.
• Uses: α-D-Galactose 1-Phosphate is the phosphate conjugate of α-D-Galactose G155260, a natural aldohexose which is ubiquitous in bacteria, plants, and animals, including human brains.

Technology Process of ALPHA-D-GALACTOSE-1-PHOSPHATE DIPOTASSIUM SALT DIHYDRATE

There total 2 articles about ALPHA-D-GALACTOSE-1-PHOSPHATE DIPOTASSIUM SALT DIHYDRATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

α-D-galactose-1-phosphate (59-56-3,2240-08-6,2255-14-3,2520-52-7,6799-01-5,10456-01-6,14048-34-1,15978-07-1,19993-19-2,20299-62-1,40591-51-3,62057-78-7,77280-79-6,78341-19-2,27251-84-9,63779-58-8,262856-84-8) → α-D-galactopyranosyl phosphate dipotassium salt (19046-60-7)

Guidance literature:

With potassium hydroxide; pH=8.5;

DOI:10.1016/j.carres.2014.10.014

Reference yield:

D-Galactose (10257-28-0) → α-D-galactopyranosyl phosphate dipotassium salt (19046-60-7)

Guidance literature:

Multi-step reaction with 2 steps

1: phosphoenolpyruvic acid monosodium salt; magnesium chloride; adenosine 5'-triphosphate disodium salt; pyruvate kinase; galactokinase / 24 h / 30 °C / Enzymatic reaction

2: potassium hydroxide / pH 8.5

With galactokinase; pyruvate kinase; phosphoenolpyruvic acid monosodium salt; adenosine 5'-triphosphate disodium salt; potassium hydroxide; magnesium chloride;

DOI:10.1016/j.carres.2014.10.014

Reference yield:

α-D-Glucose 1-phosphate dipotassium salt (2040-69-9,6736-77-2,16419-25-3,19046-60-7,53823-71-5,71888-67-0,89798-48-1,91502-59-9,105751-36-8,133841-18-6) → Potassium α-D-glucopyranosiduronate 1-(dipotassium phosphate) (71662-14-1)

Guidance literature:

With 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hydroxide; sodium hypochlorite; Dowex 5x8; In water; for 1.5h; other reagent;

DOI:10.1016/S0008-6215(97)00030-X

upstream raw materials:

α-D-galactose-1-phosphate

D-Galactose

Downstream raw materials:

Potassium α-D-glucopyranosiduronate 1-(dipotassium phosphate)

ammonium P¹-moraprenyl, P²-α-D-glucopyranosyl pyrophosphate

ammonium P¹-moraprenyl, P²-α-D-galactopyranosyl pyrophosphate

Refernces