1,3-Dithiane-2-carboxylic acid methylester

Base Information

• Chemical Name: 1,3-Dithiane-2-carboxylic acid methylester
• CAS No.: 56579-84-1
• Molecular Formula: C6H10 O2 S2
• Molecular Weight: 178.2724
• Mol file: 56579-84-1.mol

Synonyms:2-(Methoxycarbonyl)-1,3-dithiane;Methyl 1,3-dithiane-2-carboxylate; NSC 241856

Chemical Property of 1,3-Dithiane-2-carboxylic acid methylester

Chemical Property:

• Vapor Pressure: 0.00873mmHg at 25°C
• Boiling Point: 266.3°Cat760mmHg
• Flash Point: 124°C
• PSA: 76.90000
• Density: 1.246g/cm³
• LogP: 1.35560

Purity/Quality:

99%min ^*data from raw suppliers

methyl1,3-dithiane-2-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,3-Dithiane-2-carboxylic acid methylester

There total 2 articles about 1,3-Dithiane-2-carboxylic acid methylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

methanol (67-56-1) + 1,3-dithiane-2-carboxylic acid (20461-89-6) → methyl 1,3-dithiane-2-carboxylate (56579-84-1)

Guidance literature:

With hydrogenchloride; for 0.0833333h;

DOI:10.1016/S0040-4020(01)87344-0

Reference yield:

→ methyl 1,3-dithiane-2-carboxylate (56579-84-1)

Guidance literature:

Reference yield: 95.0%

methyl 1,3-dithiane-2-carboxylate (56579-84-1) + 3-(p-methoxyphenyl)-2-propen-1-yl methyl carbonate (488151-80-0) → C16H20O3S2

Guidance literature:

With potassium phosphate; bis(1,5-cyclooctadiene)diiridium(I) dichloride; 1,3,4,6,7,8-hexahydro-2H-pyrimido[1,2-a]pyrimidine; potassium tert-butylate; (3,5-dioxa-4-phospha-cyclohepta[2,1-a;3,4-a']dinaphthalen-4-yl)-bis-(1-phenyl-ethyl)-amine; In tetrahydrofuran; at 50 ℃; for 6h; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.joc.0c01683

upstream raw materials:

methanol

1,3-dithiane-2-carboxylic acid

Downstream raw materials:

2-[1-(2,2-Dimethyl-propionyloxy)-2-phenyl-propyl]-[1,3]dithiane-2-carboxylic acid methyl ester

2-[(2,2-Dimethyl-propionyloxy)-p-tolyl-methyl]-[1,3]dithiane-2-carboxylic acid methyl ester

2-[1-(2,2-Dimethyl-propionyloxy)-2-phenyl-ethyl]-[1,3]dithiane-2-carboxylic acid methyl ester

2-[(2,2-Dimethyl-propionyloxy)-phenoxy-methyl]-[1,3]dithiane-2-carboxylic acid methyl ester

Refernces

• 1、 -. "1-Carba-6-(1-hydroxyethyl)-2-carbonyl-penem-3-carboxylic acid and preparation thereof". . . Retrieved 2008/06/13.