OXALYL BROMIDE

Base Information

• Chemical Name: OXALYL BROMIDE
• CAS No.: 15219-34-8
• Molecular Formula: C2Br2O2
• Molecular Weight: 215.829
• Hs Code.: 2917.19
• European Community (EC) Number: 239-271-7
• NSC Number: 96957
• UNII: YZQ2D2RT2Q
• DSSTox Substance ID: DTXSID9065869
• Nikkaji Number: J218.380C
• Wikidata: Q81992471
• Mol file: 15219-34-8.mol

Synonyms:OB;OXALYL BROMIDE;BrCOCOBr;Ethanedioyl bromide;ethanedioyldibromide;Ethanedioyl-dibromide-;OXALYL BROMIDE, 2.0M SOLUTION IN DICHLOR OMETHANE;Oxaly bromide

Chemical Property of OXALYL BROMIDE

Chemical Property:

• Appearance/Colour: clear yellow to yellow-green liquid
• Vapor Pressure: 16.8mmHg at 25°C
• Melting Point: -19 °C
• Refractive Index: n20/D 1.522(lit.)
• Boiling Point: 118.3 °C at 760 mmHg
• Flash Point: 109.8 °C
• PSA: 34.14000
• Density: 2.627 g/cm³
• LogP: 0.82940
• Storage Temp.: Refrigerator (+4°C)
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 215.82446
• Heavy Atom Count: 6
• Complexity: 75.5

Purity/Quality:

98%,99%, ^*data from raw suppliers

Oxalyl Bromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C,T
• Hazard Codes: C,T
• Statements: 23/24/25-34-40-29-20-14-37
• Safety Statements: 26-36/37/39-45-28-27

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Other Classes -> Halogenated Ketones
• Canonical SMILES: C(=O)(C(=O)Br)Br
• Uses: Used in synthetic applications of carbon-substituted iminium saltsReactant for:Synthesis of mutasynthons added to cultures of A. pretiosum for mutasynthetic generation of ansamitocin derivativesOxalic acid formation from hydroxyl radical substitutionsCyclization to produce CRF1 receptor antagonistsPreparation, optical and electrochemical studies of thiophene end capped olig(2,3-alkylthieno[3,4-b]pyrazine)Asymmetrical synthesis of glycosyl chlorides and bromides Leptin from rat has been used:to check the effect of intranasal nerve growth factor (NGF) on NGF activity in the spinal cord of Sprague-Dawley ratsfor validation of labelling for leptin-bearing cells of Sprague-Dawley ratsto study the effect of leptin on STAT3 (signal transducer and activator of transcription 3) phosphorylation in neural population of Sprague-Dawley ratsto study leptin response towards chemoreflex in nucleus of the solitary tractin rats, to check the effect of association between leptin and neuronal nitric oxide pathway on penicillin-induced epileptiform activity

Technology Process of OXALYL BROMIDE

There total 4 articles about OXALYL BROMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

oxalyl dichloride (79-37-8) → Oxalyl bromide (15219-34-8)

Guidance literature:

With trimethylsilyl bromide; for 1.5h;

DOI:10.1055/s-1981-29390

Reference yield:

acetylene dibromide (624-61-3) + ethanol (64-17-5) → 1,1,2,2-tetrabromoethene (79-28-7) + Oxalyl bromide (15219-34-8) + ethyl dibromoacetate (617-33-4)

Guidance literature:

Reference yield:

oxalic acid (144-62-7,97993-78-7) → Oxalyl bromide (15219-34-8)

Guidance literature:

With phosphorus pentabromide; phosphorus(V) oxybromide;

upstream raw materials:

oxalyl dichloride

oxalic acid

hydrogen bromide

acetylene dibromide

Downstream raw materials:

carbon dioxide

hydrogen bromide

bromine

2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl bromide

Refernces