Methanol, (methylthio)-, benzoate

Base Information

• Chemical Name: Methanol, (methylthio)-, benzoate
• CAS No.: 19207-88-6
• Molecular Formula: C9H10O2S
• Molecular Weight: 182.243
• Mol file: 19207-88-6.mol

Synonyms:

Chemical Property of Methanol, (methylthio)-, benzoate

Chemical Property:

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methanol, (methylthio)-, benzoate

There total 18 articles about Methanol, (methylthio)-, benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

dimethyl sulfoxide (67-68-5,8070-53-9) + benzoic acid (65-85-0,8013-63-6) → benzoyloxy-methylsulfanyl-methane (19207-88-6)

Guidance literature:

With t-butyl bromide; sodium hydrogencarbonate; at 25 - 30 ℃; for 24h; Mechanism; the similar reactions with a series of carboxylic acids and N-protected amino-acids; no desired products with other t-BuHal (Hal=Cl,I); other weak base (Et₃N) is suitable;

DOI:10.1039/P19810002737

Reference yield: 97.0%

dimethylsulfide (75-18-3) + benzoic acid (65-85-0,8013-63-6) → benzoyloxy-methylsulfanyl-methane (19207-88-6)

Guidance literature:

With tetrabutylammonium tetrafluoroborate; In methanol; acetonitrile; at 20 ℃; for 6h; Inert atmosphere; Electrochemical reaction;

DOI:10.1021/jacs.1c00288

Reference yield: 81.0%

benzoyl chloride (98-88-4) + dimethyl sulfoxide (67-68-5,8070-53-9) → benzoyloxy-methylsulfanyl-methane (19207-88-6)

Guidance literature:

With iron(III) oxide; triethylamine; In toluene; at 20 ℃; for 2h; Reagent/catalyst; Solvent; Temperature; Inert atmosphere;

DOI:10.1016/j.tetlet.2017.04.053

upstream raw materials:

phenyl isocyanate

dimethyl sulfoxide

benzoic acid

benzene

Downstream raw materials:

methylsulfonylmethyl benzoate

Refernces

• 1、 Yu, Subeen,Nam, Kye Chun,Lee, Sunwoo. "Synthesis of Methylthiomethyl Esters by the Reaction of Carboxylic Acid with Dimethylsulfoxide". . p. 906 - 908. Retrieved 2018.
• 2、 Carvalho, Bernardo Basbaum Portinho De Puga,Amaral, Adriane Antonia Pereira,De Castro, Pedro P?ssa,Ferreira, Fernanda Cerqueira Moreira,Horta, Bruno Araújo Cautiero,Amarante, Giovanni Wilson. "On the development of a nucleophilic methylthiolation methodology". . p. 5420 - 5426. Retrieved 2020/08/03.